摘要
目的 为了进一步控制淫羊藿药材质量 ,对朝鲜淫羊藿 Epimedium koreanum总黄酮部位进行系统的化学成分研究。方法 采用反复硅胶柱色谱分离得到 13个化合物 ,通过理化常数和波谱分析方法鉴定了其结构。结果 分别为宝藿苷 - I( )、淫羊藿次苷 - I( )、epimedoside C( )、淫羊藿定 B( )、淫羊藿苷 ( )、金丝桃苷 ( )、hexandraside E ( )、脱水淫羊藿素 ( )、麦芽酚 ( )、去甲基脱水淫羊藿素 ( )、肌醇 ( )、epimedoicarisoside A( )和 (+) - cycloolivil( )。结论 化合物 、 、 为首次从朝鲜淫羊藿中分离得到 ,其中化合物
Object In order to control the quality of crude drug, the total flavonoids of Epimedium koreanum Nakai were investigated Methods By repeated chromatographic methods 13 compounds were isolated and purified, and their structures were elucidated by physicochemical properties and spectroscopic methods (UV, IR, 1HNMR, 13 CNMR, HMBC, EI MS) Results They were identified as icariside II (Ⅰ), icariside I (Ⅱ), epimedoside C (Ⅲ), epimedin B (Ⅳ), icariin (Ⅴ), hyperoside (Ⅵ), hexandraside E (Ⅶ), anhydroicaritin (Ⅷ), maltol (Ⅸ), demethylanhydroicaritin (Ⅹ), insistol (Ⅺ), epimedoicarisoside A ( ⅩⅡ ) and (+) cycloolivil ( ⅩⅢ ) Conclusion Compounds Ⅶ, Ⅺ, ⅩⅢ were isolated from E koreanum for the first time, and Ⅶ was obtained from the plants of Epimedium L for the first time
出处
《中草药》
CAS
CSCD
北大核心
2002年第11期964-967,共4页
Chinese Traditional and Herbal Drugs
基金
国家"九五"攻关项目 (99-92 9-0 1-3 1)
