摘要
目的 :评价 0 2 5 %罗比卡因应用于小儿骶管阻滞的安全性和有效性。方法 :80例 1～ 8岁 ,行下肢、会阴手术患儿随机分为两组 :罗比卡因组 (R组 ,n =4 0 )和布比卡因组 (B组 ,n =4 0 )。两组均在基础麻醉后行骶管阻滞 ,分别注入 0 2 5 %罗比卡因 (R组 )和 0 2 5 %布比卡因 (B组 ) 0 8ml kg。测定骶管阻滞的起效时间和镇痛时间 ,记录HR、MAP和SpO2 及追加镇痛药 ,并观察出现的副反应。结果 :各组术中均无须追加镇痛药 ,麻醉效果满意。R组与B组的起效时间 (7 6± 2 3minvs 8 2±2 6min)和镇痛时间 (32 2± 4 7minvs 2 98± 6 5min)相比较 ,均无显著性差异 (P >0 0 5 )。未观察到局麻药的毒性反应。结论 :0 2 5 %罗比卡因 (0 8ml kg)可提供满意的小儿骶管阻滞麻醉 ;同浓度、同剂量的罗比卡因和布比卡因用于小儿骶管阻滞 。
Objective:To evaluate the clinical efficacy and reliability of 0 25% ropivacaine in paediatric caudal block.Methods:80 children aged 1～8 yr undergoing elective lower limb or perinei surgery were randomly allocated to receive caudal block of 0 8ml/kg of either 0 25% ropivacaine(R group,n=40)or 0 25% bupivacaine(B group,n=40).All blocks were placed after induction of light general anaesthesia.Parameters investigated included onset time and analgesia duration of the cadual block.Heart rate,arterial pressure and oxygen saturation were measured every 5 min after administration of local anaesthetic.Adding analgesic and its adverse events were recorded.Results:No further analgesic were required during operation in the two groups.Onset times(R group:7 6±2 3min,B group:8 2±2 6min)and analgesia duration(R group:322±47min;B group:298±65min)were not significantly different between the two groups(p>0 05).No adverse events were observed.Conclusions:0 25% ropivacaine(0 8ml/kg)is well tolerated and provides effective analgesia when given for paediatric caudal block.Ropivacaine produces similar effect as bupivacaine with equal concentration and dosage.
出处
《广西医学》
CAS
2003年第1期5-6,共2页
Guangxi Medical Journal
关键词
罗比卡因
骶管阻滞
小儿
麻醉
布比卡因
Ropivacaine
Caudal block
Anesthesia,paediatric
Bupivacaine
