摘要
1987～1990年,我们以青海省互助土族自治县东和乡的43个自然村,6046人的原地方性甲状腺肿中等病区为样本,以儿童亚临床克汀病流行病学调查为基础,观察了缺碘对人类危害的谱带现象。发现碘缺乏损害自胚胎期至生后期的序列为:克汀病、单纯聋哑、亚临床克汀病、精神发育迟滞;地方性甲状腺肿、激素性甲低,婴儿死亡率增高、性发育落后和生殖衰退。谱带还可分为典型临床型和非典型临床型两类。提示应根据缺碘对人群的危害谱带有针对性地实施预防措施。
During 1988-1990,we observed the spectrum of IDD based on survey of subcretinism in children from 8 villages with 6 064 people in a mild endemic goiter areas.The sequence of impairments of IDD were found from prenatal to postnatal: cretinism, simple deaf-mutism, subcretinism, mental retardation, goiter, thyroid hormone deficieny,increased infant mortality, reproductive failure and delayed sexual maturity. The spectrum of disorders also can be divided into typical clinical types and non-clinical types. This survey indicated that after 10 years of iodine prophylaxis, the clinical impairments have been under control, but the subclincal impairments were still exist. It is suggested in this paper that IDD control be carried out more deeply, and the prophylaxis concentrate on the current problems.
出处
《地方病通报》
1992年第4期19-22,共4页
Endemic Diseases Bulletin
关键词
碘缺乏
青海
克汀病
Iodine deficiency area
Qinghai
Iodine deficiency disorders(IDD)
IDD impairment spectrum
Human
