摘要
本文报告了本室五年来收治的7例肝泡球蚴病,占同期肝细粒棘球蚴病的1.76％(7/396),其中6例手术治疗。患者均来自新疆牧区,男5例,女2例。4例为哈萨克族,其他民族3例。其临床表现及肝功化验酷似肝癌,可根据流行病学史和病程的长短及临床症状、包虫血清免疫学试验和AFP检测结果,特别是B超、CT及X光检查的特殊征象可确诊,易与肝癌鉴别。手术是本病的主要治疗方法。6例手术治疗者中仅1例行根治性肝叶切除术,其余5例行姑息性病灶切除或活检术,主要原因是临床发现的病人多为晚期患者。不能手术根治。故应加深对本病的认识,尽早就医,采用上述综合性诊断方法,能早期确诊早期手术治疗。对手术前后以及不能手术的患者均予以丙硫咪唑药物化疗,本组按20mg/kg/d分两次口服,至少3～6个月,未发现明显副作用。一例根治性手术患儿和一例活检患者随访2.5年均成活。另外,本文重点讨论了关于本组包虫免疫试验假阴性率比一般文献报告高的原因,以及对本病临床诊断标准与分期的建议。
The authors report here seven cases of alveolar echinococcosis admitted in the last five years. It was 1.76% (7 / 396) in all the cases with hydatid disease in this course. All of these cases came from the pastoral areas of Xinjiang. They were easely diagnosed and differentiated from cancer of the liver by CT, ultrasonography, X-ray and laboratory examination. Only two cases were treated by lobectomy of the liver. Five cases were treated by palliative operation because they are delayed to occur. Chemotherapy with albendazol at a dose of 20 mg / kg / d was implemented for at least 3-6 months without any side effects. The authors proposed the standards for clinical diagnosis and clinical stages.
出处
《地方病通报》
1992年第3期99-102,共4页
Endemic Diseases Bulletin
关键词
泡球蚴病
肝
外科手术
Alveolar echinococcosis
Liver
Surgery
