摘要
本文研究了陕西省1970~1990年8个地市的29个县176个村队之大骨节病区14382例儿童手指骨变化与年龄的关系,发现病区儿童手指骨X线患病率及患者骨端病灶性改变,随年龄增长在增高;干骺端病灶性改变随患者年龄增长在下降,治愈增多。观察7年的1184例患儿手片,看出大骨节病可以自然修复和痊愈,修复率为68.17%,痊愈率为45.45%,同时显示大骨节病骨端型改变在儿童时期不会首先发病,单独骨端型改变是干骺端病变治愈结果。由此推断致病因子的作用为一次性打击作用,病灶的反复则为二次作用引起。故,依靠干骺端改变判定药物疗效和论述病因,应科学谨慎。
In an attempt to elucidate the relationship between the evolving process of X-ray signs of children's hands with Kashin-Beck disease and age, we analysed 14382 X-ray hand-films of the children with Kashin-Beck disease in 29 counties in Shaanxi Province, the results showed that the rate of positive metaphyseal findings varied inversely with age, in contrast, the rate of positive findings of distal end of bone varied proportionally with age. Our data are of certain significance for the prevention and cure of the disease.
出处
《地方病通报》
1992年第3期84-86,共3页
Endemic Diseases Bulletin
关键词
大骨节病
病因学
儿童
发病率
Kashin-Beck disease
Metaphysis
Distal end of bone