摘要
The development of efficient and safe taste-enhancing compound is important to reduce sodium intake,at the same time maintains food palatability.Hence,in this study,an excellent and safe taste-enhancing compound(N’-[(2,4-dimethoxyphenyl)methyl]-N-(2-pyridin-2-ylethyl)oxamide(DE))was synthesized in 96%yield under optimized conditions.The chemical structure of DE was clearly characterized by^(1)H and^(13)C NMR spectrum.Human sensory evaluation showed that the addition of DE(0.9 ppm)significantly enhanced the kokumi,umami,and salt tastes,the degree of enhancement by 66.4%,56.6%,and 26.2%,respectively.The result of electronic tongue was consistent with the human sensory evaluation,which was again illustrated that DE is a promising taste-enhancer.Time-intensity(TI)results revealed that the sample(with addition of 0.9 ppm DE)umami duration(210.0±0 s)were significantly prolonged that of control group(150.0±0 s).Moreover,the DE could bind and activate calcium-sensing and T1R1/T1R3 receptors,inducing stronger umami and kokumi tastes.This work revealed the potential of DE as an excellent taste enhancer.
基金
supported by the National Natural Science Foundation of China(No.31201416)
111 Project(No.B17018).
