摘要
目的观察黄芪桂枝青藤汤联合偏瘫五针对卒中后感觉障碍患者的临床疗效。方法选取2021年7月至2023年7月收治的90例卒中后感觉障碍患者为研究对象,按照随机数字表法分为对照组和研究组,各45例。对照组采用偏瘫五针法治疗,研究组应用黄芪桂枝青藤汤联合偏瘫五针法治疗。2组均治疗4周后统计疗效,比较2组治疗前后感觉功能评分、自理能力评分、神经功能评分、精神状态评分[包括汉密尔顿焦虑量表(HAMA)与汉密尔顿抑郁量表(HAMD)]、中医证候评分(包括半身不遂、言语謇涩、肢体麻木、肌肤不仁)变化情况,比较2组治疗期间不良反应发生情况。结果与本组治疗前比较,2组治疗后感觉功能评分、自理能力评分均升高(P<0.05),神经功能评分均降低(P<0.05),且研究组治疗后感觉功能评分、自理能力评分均高对照组(P<0.05),神经功能评分低于对照组(P<0.05)。与本组治疗前比较,2组治疗后精神状态HAMA评分、HAMD评分均降低(P<0.05),且研究组治疗后HAMA评分、HAMD评分均低于对照组(P<0.05)。与本组治疗前比较,2组治疗后中医证候半身不遂、言语謇涩、肢体麻木、肌肤不仁评分均降低(P<0.05),且研究组治疗后半身不遂、言语謇涩、肢体麻木、肌肤不仁评分均低于对照组(P<0.05)。研究组总有效率91.11%(41/45),对照组总有效率71.11%(32/45),研究组总有效率高于对照组(P<0.05)。研究组不良反应总发生率11.10%(5/45),对照组不良反应总发生率13.33%(6/45),2组不良反应总发生率比较差异无统计学意义(P>0.05)。结论黄芪桂枝青藤汤联合偏瘫五针联合治疗卒中后感觉障碍疗效确切,能显著改善患者感觉功能,提高自理能力,改善神经功能,缓解焦虑抑郁情绪,安全可靠。
Objective To investigate the clinical efficacy of Huangqi Guizhi Qingteng Decoction and five needles for hemiplegia in treating patients with post-stroke sensory disorders.Methods A total of 90 patients with post-stroke sensory disorders treated in our hospital from July 2021 to July 2023 were randomly separated into a control group(n=45)and a study group(n=45).All patients were treated with the five needles for hemiplegia,while those in the study group were additionally treated with a combination of Huangqi Guizhi Qingteng decoction,and the patients in the both groups were treated for 4 weeks.The primary endpoint of the study was sensory function score,self-care ability score,neurological function score,mental state score(Hamilton anxiety scale[HAMA]and Hamilton depression scale[HAMD]),traditional Chinese medicine(TCM)syndrome score(dimension score of hemiplegia,speech acerbity,limb numbness,skin numbness)before and after treatment between groups.The secondary endpoint was treatment-emergent adverse events(TEAEs)in the two groups.Results After treatment,significantly increased scores of sensory function and self-care ability,and decreased scores of neurological function were detected in the both groups than those before treatment,the improvements were more pronounced in the study group than the control group(P<0.05).The mental state score(HAMA and HAMD)and TCM syndrome score(dimension score of hemiplegia,speech acerbity,limb numbness,skin numbness)in the both groups were significantly decreased than those before treatment(P<0.05),and showing greater reductions in the study group than control group(P<0.05).The total effective rates of the study group was significantly higher than that of the control group(91.11%[41/45]vs 71.11%[32/45],P<0.05),but the difference in TEVEs was not significant between the study group and the control group(11.10%[5/45]vs 13.33%[6/45],P>0.05).Conclusion The combination therapy of Huangqi Guizhi Qingteng Decoction and five needles for hemiplegia can significantly alleviate the clinical symptoms of post-stroke sensory disorders,improve self-care ability,enhance neurological function,relieve anxiety and depression,and it is a safety and reliable method.
作者
汪灵
王培峻
龚志荣
WANG Ling;WANG Peijun;GONG Zhirong(Department of Rehabilitation,Linshui County Hospital of Chinese Medicine,Guangan,Sichuan 638500)
出处
《河北中医》
2026年第4期633-636,641,共5页
Hebei Journal of Traditional Chinese Medicine
基金
四川省中医药管理局科学技术研究专项课题(编号:2023MS058)。
关键词
卒中后遗症
感觉障碍
中药疗法
针刺疗法
Post-stroke sequelae
Sensory disorders
Traditional Chinese medicine therapy
Acupuncture therapy
