摘要
目的调查医护人员和患者对药物性肝损伤(drug induced liver injury,DILI)的认知情况。方法选取杭州市红十字会医院的医护人员和2022年2月至2023年12月就诊于杭州市红十字会医院的普通患者共417人作为研究对象,分为医生组(n=97),护士组(n=110)与患者组(n=216)。采用本研究团队自行设计的问卷,调查医护人员(医生、护士)和患者对DILI的认知度。结果75.2%的被调查者认可药物可致肝损伤,其中医生、护士的认知度显著高于患者;58.4%的被调查者知晓DILI可致死亡,且医生、护士的认知度远高于患者;用药安全行为方面,83.7%的被调查者会主动查看药物说明书,5.2%的被调查者有DILI病史。结论医护人员与患者对药物肝毒性的认知差距较显著,尤其在中草药及保健品相关肝毒性方面。
Objective To investigate the awareness of drug-induced liver injury(DILI)among medical staff and patients.Methods Medical professionals from Hangzhou Red Cross Hospital and general patients who visited Hangzhou Red Cross Hospital from February 2022 to December 2023 were enrolled as study subjects,they were divided into three groups:physicians(n=97),nurses(n=110),and patients(n=216).A self-designed questionnaire by the research team was used to assess the awareness of DILI among physicians and nurses and patients.Results 75.2%of the respondents acknowledged that medications can cause liver injury,with physicians and nurses demonstrating significantly higher awareness than patients.58.4%of the respondents were aware that DILI can lead to death,and physicians and nurses exhibited markedly higher awareness than patients.Regarding medication safety behaviors,83.7%of the respondents would proactively review drug package inserts.5.2%of the respondents had a history of DILI.Conclusion There is a significant gap in the understanding of drug-induced hepatotoxicity among medical professionals,particularly regarding the hepatotoxicity associated with traditional Chinese herbal medicines and health supplements.
作者
刘肄辉
郭艳
冯慧
徐虹
吴之茵
韩颖
潘锋
LIU Yihui;GUO Yan;FENG Hui;XU Hong;WU Zhiyin;HAN Ying;PAN Feng(Department of Gastroenterology,Hangzhou Red Cross Hospital,Hangzhou 310003,Zhejiang,China;Department of Gastroenterology,Hangzhou Third Hospital,Hangzhou 310009,Zhejiang,China)
出处
《中国现代医生》
2026年第5期54-57,共4页
China Modern Doctor
基金
浙江省中医药科研基金项目(2024ZL697)。
关键词
药物性肝损伤
认知度
调查研究
Drug-induced liver injury
Awareness
Survey study
