摘要
目的比较丙泊酚静脉麻醉与地氟烷吸入麻醉对非心脏手术患者术后急性疼痛与睡眠的影响,为优化术后康复提供依据。方法选择2019年8月至2021年4月在首都医科大学附属北京朝阳医院行非心脏手术的250例患者为研究对象,根据术中麻醉维持方式将其分为静脉组和吸入组。静脉组术中采用丙泊酚2~6 mg/(kg·h)联合瑞芬太尼0.1~0.5μg/(kg·min)持续静脉输注,吸入组采用地氟烷吸入维持2%~8%联合瑞芬太尼0.1~0.5μg/(kg·min)持续静脉输注。比较两组视觉模拟评分法(VAS)评分、术后恶心呕吐(PONV)评分、失眠严重程度指数(ISI)评分、手术时间、住院时间。结果倾向性评分匹配后,两组各纳入40例患者。两组术后第1~3天VAS评分和PONV评分比较,差异无统计学意义(P>0.05)。两组手术时间、住院时间比较,差异无统计学意义(P>0.05)。静脉组术后第1天ISI评分高于吸入组,差异有统计学意义(P<0.05)。两组患者满意度评分比较,差异无统计学意义(P>0.05)。结论丙泊酚静脉麻醉相较于地氟烷吸入麻醉可增加术后第1天ISI评分。本研究可为临床医师深入了解围手术期睡眠与疼痛及麻醉方式的影响提供参考,并为提高患者术后睡眠质量、缓解术后疼痛和加速康复提供科学依据。
Objective To compare the effects of intravenous anesthesia with Propofol and inhalation anesthesia with Desflurane on postoperative acute pain and sleep in patients undergoing non-cardiac surgery,and to provide a basis for optimizing postoperative rehabilitation.Methods A total of 250 patients who underwent non-cardiac surgery at Beijing Chao-Yang Hospital,Capital Medical University from August 2019 to April 2021 were selected as the research subjects and they were divided into intravenous group and inhalation group according to the intraoperative anesthesia maintenance methods.In the intravenous group,Propofol at a dose of 2-6 mg/(kg·h)combined with Remifentanil at a dose of 0.1-0.5μg/(kg·min)was continuously intravenously infused during the operation;and in the inhalation group,Desflurane inhalation maintained at 2%-8%combined with Remifentanil at a dose of 0.1-0.5μg/(kg·min)was continuously intravenously infused.The visual analogue scale(VAS)score,postoperative nausea and vomiting(PONV)score,insomnia severity index(ISI)score,operation time,and hospital stay were compared between the two groups.
作者
张舰
段晓峰
孙祎
许杰
ZHANG Jian;DUAN Xiaofeng;SUN Yi;XU Jie(Department of Anesthesiology,Beijing Chao-Yang Hospital,Capital Medical University,Beijing 100020,China)
出处
《中国医药导报》
2026年第6期26-30,共5页
China Medical Herald
基金
国家自然科学基金资助项目(82401392)。
关键词
静脉麻醉
吸入麻醉
非心脏手术
睡眠
疼痛
Intravenous anesthesia
Inhalation anesthesia
Non-cardiac surgery
Sleep
Pain
