摘要
Sepsis is defined as life-threatening organ dysfunction secondary to a dysregulated host response to infection.[1]Sepsis was responsible for approximately 20%of deaths worldwide before the corona virus disease pandemic and has been characterized as a global health priority by the World Health Organization.[2]Therapy for sepsis is characterized by rapid initiation of antimicrobial therapy,fluid resuscitation,and non-specific supportive care.[3]Antimicrobial therapy is subsequently tailored if an inciting organism is identified or specific organisms are confidently ruled out.International guidelines,such as the Surviving Sepsis Campaign,have been associated with improved outcomes by putting together a compendium of evidence-based recommendations based on GRADE methodology.
基金
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
