摘要
Acute hypoxemic respiratory failure(AHRF)refers to“de novo”respiratory failure,excluding cardiogenic pulmonary edema or exacerbation of chronic lung diseases.AHRF can be defined as the arterial pressure of oxygen/inspiratory fraction of oxygen(PaO_(2)/FiO_(2))≤300 mmHg in patients receiving oxygen therapy.[1]Whereas FiO_(2)cannot be measured under a standard oxygen mask,it can be best estimated using the following formula:FiO_(2)(%)=flow of oxygen(L/min)×3+21%.[2]Several oxygenation strategies can be proposed as an alternative to standard oxygen in patients with AHRF,including highflow nasal cannula oxygen(HFNC),continuous positive airway pressure(CPAP),and noninvasive ventilation(NIV).