摘要
目的观察在尿路感染诊断中应用细菌定量计数联合尿沉渣白细胞检验的价值。方法选取2024年6月-10月于本院就诊的100例尿路感染疑似患者作为观察对象。所有病例均同步接受细菌定量计数与尿沉渣白细胞检测。研究以尿液细菌培养结果为参照标准,并对培养结果进行统计分析。此外,对不同检验方法阳性率和诊断效能、不同检测方法对尿路感染诊断准确率与尿细菌培养结果的一致性进行分析,并采用ROC曲线分析不同检验方法对尿路感染诊断。结果尿细菌培养结果显示,100例样本检出阳性83例,阳性率为83.00%,主要病原菌为大肠埃希菌,其次为链球菌、葡萄球菌;联用细菌定量计数与尿沉渣白细胞检查的阳性检出率为81.00%,高于单一细菌定量计数(74.00%)或单纯尿沉渣白细胞检验(69.00%)(P<0.05),而单独两种方法的阳性率无差异(P>0.05);在诊断效能(包括敏感度、特异度、阳性和阴性预测值)方面,相比单一检测,联合应用细菌定量计数与尿沉渣白细胞检验更具优势(P<0.05);细菌定量计数+尿沉渣白细胞检验与尿培养结果具有一致性;ROC曲线分析结果显示,尿沉渣白细胞检验的AUC为0.847,细菌定量计数为0.892,二者联合检验的AUC为0.965。结论尿路感染诊断中,细菌定量计数与尿沉渣白细胞联检在敏感度与特异度方面均表现出良好性能,同时与尿细菌培养一致性较高。
Objective To observe the application value of quantitative bacterial count combined with urinary sediment white blood cell test in the diagnosis of urinary tract infection.Methods A total of 100 patients with suspected urinary tract infection who were treated in our hospital from June to October 2024 were selected as observation objects.All cases received simultaneous bacterial quantitative count and urine sediment white blood cell detection.The results of urine bacterial culture were used as the reference standard,and the results were statistically analyzed.In addition,the positive rate and diagnostic efficiency of different test methods,the consistency between the diagnostic accuracy of different test methods for urinary tract infection and the results of urine bacterial culture were analyzed,and the ROC curve was used to analyze the diagnosis of urinary tract infection by different test methods.Results The results of urine bacterial culture showed that 83 cases were positive in 100 samples,with a positive rate of 83.00%.The main pathogenic bacteria were Escherichia coli,followed by Streptococcus and Staphylococcus.The positive rate of bacterial quantitative count+urine sediment white blood cell detection was 81.00%,which was higher than 74.00%of bacterial quantitative count and 69.00%of urine sediment white blood cell test(P<0.05),however,no statistically significant difference was observed in the positive rates of the two methods(P>0.05).Compared with single detection,the combined application of bacterial quantitative count and urinary sediment white blood cell test showed advantages in various diagnostic efficacy indexes(including sensitivity,specificity,positive and negative predictive values),and the difference was statistically significant(P<0.05).The results of bacterial quantitative count+urine sediment white blood cell test were consistent with those of urine culture.ROC analysis revealed that the AUC for urinary sediment WBC count was 0.847,for bacterial quantitative count was 0.892,and for the combined test reached 0.965.Conclusion In the diagnosis of urinary tract infection,the combined detection of bacterial quantitative count and urinary sediment white blood cell has good performance in sensitivity and specificity,and has high consistency with urinary bacterial culture.
作者
袁雁平
YUAN Yanping(Tianjin Hexi District Maternity and Children′s Hospital,Tianjin 300202,China)
出处
《医学信息》
2026年第4期162-165,共4页
Journal of Medical Information
关键词
尿路感染
细菌定量计数
尿沉渣白细胞检验
Urinary tract infection
Bacterial quantitative count
Urinary sediment white blood cell test
