摘要
目的分析老年2型糖尿病(type 2 diabetes mellitus,T2DM)患者并发视网膜病变的相关因素及判别效能。方法回顾性分析2022年4月至2025年4月在北京航天总医院治疗的314例老年T2DM患者,采用logistic回归分析影响老年T2DM患者并发视网膜病变的相关因素,并采用ROC曲线分析相关因素的判别效能。结果与未并发组患者相比,并发组患者糖尿病病程更长,糖化血红蛋白(HbA1c)水平更高,糖尿病周围神经病变、高血压史、高度近视史、吸烟史占比更高(P<0.05);logistic回归分析显示,糖尿病病程、HbA1c、糖尿病周围神经病变、高血压史、高度近视史是老年T2DM患者并发视网膜病变的相关因素(P<0.05);基于以上相关因素建立模型进行ROC曲线分析,结果显示曲线下面积为0.935,灵敏度为0.867,特异度为0.916,95%CI:0.890~0.979。结论糖尿病病程、HbA1c、糖尿病周围神经病变、高血压史、高度近视史是老年T2DM患者并发视网膜病变的相关因素,相关因素对老年T2DM患者并发视网膜病变具有较好的判别效能。
Objective To analyze the related factors of retinopathy in elderly patients with type 2 diabetes mellitus(T2DM)and explore the discriminant efficiency.Methods A retrospective analysis was conducted on 314 elderly patients with T2DM who were treated in Beijing Aerospace General Hospital between April 2022 and April 2025.The related factors of retinopathy in elderly patients with T2DM were explored by logistic regression analysis.ROC curve was drawn to analyze the discriminant efficiency of related factors.Results Compared with the patients in the non-concurrent group,the patients in the concurrent group had a longer course of diabetes mellitus,a higher level of glycosylated hemoglobin(HbA1c),and higher proportions of diabetic peripheral neuropathy,hypertension history,high myopia history and smoking history(P<0.05).After logistic regression analysis,the course of diabetes mellitus,HbA1c,diabetic peripheral neuropathy,history of hypertension and history of high myopia were found to be related factors of retinopathy in elderly patients with T2DM(P<0.05).Based on the above related factors,a model was established for ROC curve analysis,and it was found that the area under the curve was 0.935,with sensitivity,specificity,and 95%CI being 0.867,0.916,and 0.890-0.979,respectively.Conclusion Course of diabetes mellitus,HbA1c,diabetic peripheral neuropathy,history of hypertension,and history of high myopia are related factors of retinopathy in elderly patients with T2DM.These related factors demonstrate good discriminant efficiency on retinopathy in elderly patients with T2DM.
作者
赵晓娟
李万明
ZHAO Xiaojuan;LI Wanming(Department of Ophthalmology,Beijing Aerospace General Hospital,Beijing 100076,China)
出处
《公共卫生与预防医学》
2026年第2期162-165,共4页
Journal of Public Health and Preventive Medicine
关键词
老年
2型糖尿病
视网膜病变
判别效能
Elderly
Type 2 diabetes mellitus
Retinopathy
Discriminant efficiency
