摘要
类风湿关节炎是一类慢性自身免疫性疾病,以炎症、疼痛、肿胀及关节僵硬为主要临床表现。在病情严重时可造成关节畸形和功能障碍,且该病病程迁延,致残率高,容易反复发作,对患者的生理健康与日常生活均带来显著负担。目前,西医治疗虽然能快速控制炎症、缓解疼痛,但长期应用确实存在弊端,如药物副作用、病情控制局限性、对生活质量改善的不足等。近年来,在类风湿关节炎的临床治疗中,中西医结合治疗已经发挥出其独特的优势,通过整合西医精准控炎与中医辨证施治的特点,采用中医、西医相互配伍,可减少西药用量,降低疾病活动度,减少西药不良反应,有效地改善了患者的症状及生活质量。本文综述近年来类风湿关节炎中西医结合治疗的相关研究,从中医病因病机认识、西医治疗现状、中西医结合治疗的核心策略及临床疗效证据等方面进行梳理,旨在为提高类风湿关节炎诊疗效果提供参考,同时展望未来需进一步开展大样本、长期随访的临床研究,以明确中西医结合治疗的作用机制及最佳配伍方案。
Rheumatoid arthritis(RA)is a chronic autoimmune disease characterized primarily by inflammation,pain,swelling,and joint stiffness.In severe cases,it can lead to joint deformities and functional impairment.The disease course is protracted,with a high disability rate and a tendency for recurrence,imposing significant burdens on patients’physical health and daily lives.Although Western medicine can rapidly control inflammation and alleviate pain,long-term use of such treatments presents drawbacks,including drug side effects,limited disease control,and insufficient improvement in quality of life.In recent years,integrated Traditional Chinese and Western Medicine(TCM-Western medicine)therapy has demonstrated unique advantages in the clinical management of RA.By combining the precision anti-inflammatory effects of Western medicine with the syndrome differentiation and treatment principles of TCM,this approach reduces the dosage of Western medications,decreases disease activity,minimizes adverse drug reactions,effectively improves patient symptoms and quality of life.This article reviews recent studies on integrated TCM-Western medicine therapy for RA,examining TCM etiology and pathogenesis,current Western medicine treatments,core strategies of integrated therapy,and clinical efficacy evidence.The aim is to provide references for improving RA diagnosis and treatment outcomes while advocating for future large-scale,long-term followup clinical studies to elucidate the mechanisms of action and optimal combination regimens of integrated TCM-Western medicine therapy.
作者
艾则孜木·吾提库尔
何春辉
照日格图
Aizezimu·Wutikuer;He Chunhui;Zhaorige Tu(School of Traditional Chinese Medicine,Xinjiang Medical University,Urumqi,Xinjiang 830017,China;The First Affiliated Hospital of Xinjiang Medical University,Urumqi,Xinjiang 830000,China;The Fourth Clinical Medical College of Xinjiang Medical University,Urumqi,Xinjiang 830000,China)
出处
《首都食品与医药》
2026年第6期18-22,共5页
Capital Food Medicine
关键词
中西医结合
类风湿关节炎
研究进展
Integrated Traditional Chinese and Western Medicine
Rheumatoid Arthritis
Research Progress