摘要
绝经后骨质疏松症(postmenopausal osteoporosis,PMOP)是绝经后女性常见的骨骼疾病,严重影响患者生活质量并加重家庭经济负担。中医营卫理论与人体生理病理紧密相关,“营卫交重”揭示了营气与卫气互根互用、动态平衡的关系。从营卫理论探讨,PMOP的发生与营血亏虚致骨髓失养、卫气虚弱引发免疫炎症失衡、营卫失和破坏骨稳态有关。中药如黄芪桂枝五物汤、玉屏风散、桂枝汤等,通过调和营卫、补肾健脾、活血化瘀等作用,可改善PMOP患者骨代谢、缓解症状。基于“营卫交重”从营卫理论研究PMOP防治具有重要意义,有望为临床提供新思路与新方法。
Postmenopausal osteoporosis(PMOP)is a common skeletal disorder in postmenopausal women,significantly impairing patients'quality of life and increasing family economic burdens.The Traditional Chinese Medicine(TCM)theory of Ying-Wei(nutrient-defense system)is closely related to human physiology and pathology.The concept of"dynamic balance and mutual reinforcement between Ying and Wei"(Ying-Wei Jiao-Zhong)reveals the interdependent relationship and harmonious equilibrium between Ying-Qi(nutrient Qi)and Wei-Qi(defensive Qi).From the perspective of Ying-Wei theory,the pathogenesis of PMOP may involve three aspects:deficiency of Ying-blood leading to marrow malnutrition,weakness of Wei-Qi causing immuneinflammatory imbalance,and Ying-Wei disharmony disrupting bone homeostasis.Chinese herbal formulas such as Huangqi Guizhi Wuwu Tang(Astragalus and Cinnamon Twig Five-Substance Decoction),Yupingfeng San(Jade Windscreen Powder),and Guizhi Tang(Cinnamon Twig Decoction)can improve bone metabolism and alleviate symptoms in PMOP patients through mechanisms including harmonizing Ying-Wei,tonifying kidney-spleen functions,and promoting blood circulation to remove stasis.Exploring PMOP prevention and treatment through the"Ying-Wei Jiao-Zhong"theory holds significant clinical value,offering potential novel strategies and approaches.This perspective may provide new insights for developing therapeutic interventions in clinical practice.
作者
李钰祎
熊伟
朱家钰
汪成杰
吴振宇
张泽臣
李金坤
袁一峰
刘康
史晓林
LI Yuyi;XIONG Wei;ZHU Jiayu;WANG Chengjie;WU Zhenyu;ZHANG Zechen;LI Jinkun;YUAN Yifeng;LIU Kang;SHI Xiaolin(The Second Clinical Medical School,Zhejiang University of Traditional Chinese Medicine,Hangzhou 310000,China;The Second Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310000,China)
出处
《中国骨质疏松杂志》
北大核心
2026年第2期239-244,共6页
Chinese Journal of Osteoporosis
基金
浙江省自然科学基金(LZ22H270002,ZCLQ24H2701)
浙江省中医药科技计划项目(2024ZR017)。
关键词
营卫交重
绝经后骨质疏松症
中医理论
Ying-Wei Jiao Chong
postmenopausal osteoporosis
traditional Chinese medicine theories
