摘要
To counteract small sample size,severe class imbalance and high feature redundancy in 90-day mRS prediction after stroke,this study proposes a four-stage pipeline-“ADASYN re-sampling→clinical+statistical feature screening→dimensionality reduction→5-fold cross-validation”-and benchmark composite deep-learning architectures.ADASYN first balances the minority classes in the original feature space.Next,a tri-level filter(clinical domain knowledge,variance threshold,mutual information)removes clinically meaningless or redundant variables,after which PCA compresses the remaining features while preserving critical neurological signatures(e.g.,brain-herniation history).Four hybrid CNN-RNN models are trained and compared under strict 5-fold cross-validation;the optimal ensemble yields stable,clinically interpretable probabilities that can support individualized rehabilitation planning.
基金
Shanghai University of Engineering Science Undergraduate Innovation Training Program(Project No.:cx2521005)。
