摘要
免疫系统如何在清除“外敌”的同时,确保对自身保持“宽容”,不会导致“自伤”?这个免疫学核心谜题的终极答案指向了调节性T细胞(简称Treg)。这类细胞不仅关乎如何抵御疾病,更关乎如何避免攻击自己。它们如同体内的“和平卫士”,默默维系着生命的稳态。
The 2025 Nobel Prize in Physiology or Medicine was awarded to M.E.Brunkow,F.Ramsdell,and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance.Their findings have laid the foundation for modern immune regulation theory and ushered in a new era of cell therapy.
作者
沈艺冰
范璟源
李丹
彭程
李斌
Shen Yibing;Fan Jingyuan;Li Dan;Peng Cheng;Li Bin(Shanghai Jiao Tong University School of Medicine,Shanghai Institute of Immunology,Shanghai 200001)
出处
《科学》
2025年第6期45-48,共4页
Science
