摘要
水产品作为人类重要的蛋白质来源,其全产业链面临生物毒素污染的多重风险。针对传统毒素检测方法存在的仪器依赖性强、前处理复杂、检测周期长等技术瓶颈,本文系统阐述了免疫分析法在生物毒素检测中的应用优势,重点归纳总结了真菌毒素、细菌毒素、藻类毒素和贝类毒素等主要生物毒素的特异性抗体及其免疫学检测方法的研究进展。最后,基于纳米抗体的分子特性,探讨其作为新一代检测介质在水产饲料和水产品安全检测领域的应用潜力与发展前景。本文旨在为生物毒素的快速检测技术开发提供理论参考和技术支持。
Aquatic products are essential protein sources for humans,yet their supply chains are vulnerable to various biological toxin risks.To overcome the technical challenges of conventional detection methods,such as heavy reliance on sophisticated instruments,complex sample pretreatment,and prolonged analysis time,this review systematically highlighted the benefits of immunoassays in biotoxin detection.It comprehensively summarized the research advancements in specific antibodies and immunoanalytical methods for major biotoxins,such as mycotoxins,bacterial toxins,algal toxins,and shellfish toxins.Finally,based on the molecular characteristics of nanobodies,this review explored their potential as a next-generation detection tools for monitoring aquatic feed and product safety,along with future development prospects.The findings aimed to provide theoretical insights and technical support for the development of rapid biotoxin detection technologies.
作者
谢晓筱
万红岩
李岳冰
陶飞燕
张凌晶
金腾川
曹敏杰
陈玉磊
XIE Xiaoxiao;WAN Hongyan;LI Yuebing;TAO Feiyan;ZHANG Lingjing;JIN Tengchuan;CAO Minjie;CHEN Yulei(College of Ocean Food and Biological Engineering,Jimei University,Xiamen 361021,China;Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei 230007,China)
出处
《生物学杂志》
北大核心
2026年第1期1-10,共10页
Journal of Biology
基金
国家重点研发计划项目(2024YFD2401904)
福建省自然科学基金项目(2021J01838)。
