摘要
Colorectal cancer(CRC)is a pervasive health concern worldwide,ranking third in malignancy prevalence and second in cancer-related mortality.The primary chemotherapeutic agent for CRC is 5-fluorouracil(5-Fu).Unfortunately,drug resistance is almost inevitable in patients,significantly reducing its efficacy.Therefore,underlying the mechanisms of 5-Fu resistance and exploring reversal strategies are crucial.
基金
National Natural Science Foundation of China(Grant No.:82274115)
Top Talent Support Program for Young and Middle-aged People of Wuxi Health Committee,China(Grant Nos.:BJ2023042,HB2023060)
Wuxi Medical Key Discipline,China(Grant No.:ZDXK2021002)
Associate Professor Kaisa Cui(Affiliated Hospital of Jiangnan University,China)for his kind assistance in data processing.
