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基于“心肝同治”探讨不寐辨证与机制

Pattern Differentiation and Mechanism Exploration of Insomnia Based on the Theory of Heart-Liver Simultaneous Regulation
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摘要 随着社会节奏加快和生活压力增大,不寐的发病率不断升高。但现代医学治疗本病局限性明显,而中医理论对此有着独特的优势。文章基于中医“心肝同治”理论,系统探讨了不寐(失眠)的辨证论治机制。认为“神魂一体”“气血调和”“母子相生”是该理论的生理基础,同时阐明了心肝两脏在精神情志与气血运行方面的协同作用是维持正常睡眠的关键。在此基础上,进一步解释“心肝同病”致不寐的核心病机,并列出其主要证候与对应方药。本文还从现代医学角度描述了该理论的生理机制,如神经递质系统、下丘脑垂体肾上腺轴功能、“肝脑轴”免疫炎症以及生物钟节律调节等多途径,证明了“心肝同治”多靶点干预失眠的内在联系。该理论体现中医整体观念与现代心身医学的相合,对失眠的个体化治疗具有重要指导意义,但其深入机制有待后续高质量研究进一步阐明。 With the acceleration of social rhythms and increasing life pressures,the incidence of insomnia(Bumei)has been continuously rising.While modern medicine shows significant limitations in treating this condition,traditional Chinese medicine(TCM)theory offers unique advantages.Based on the TCM theory of"Simultaneous Regulation of the Heart and Liver,"this article systematically explores the mechanisms of pattern differentiation and treatment for insomnia.It proposes that the physiological foundation of this theory lies in the"unity of the spirit and ethereal soul(Shen Hun),""harmony of Qi and blood,"and"mutual nourishment between mother and child organs(Liver Heart relationship),"while clarifying that the synergistic functions of the Heart and Liver in mental emotional activities and Qi-blood circulation are key to maintaining normal sleep.Furthermore,the core pathogenesis of insomnia resulting from"simultaneous dysfunction of the Heart and Liver"is explained,and the main clinical patterns with corresponding herbal formulas are outlined.From a modern medical perspective,this article also describes the physiological mechanisms underlying this theory through multiple pathways,such as neurotransmitter systems,hypothalamic-pituitary-adrenal(HPA)axis function,the"liver brain axis"immune inflammation pathway,and circadian rhythm regulation,demonstrating the intrinsic multi-target interventional connections of"Simultaneous Regulation of the Heart and Liver"in treating insomnia.This theory reflects the convergence of TCM's holistic concept and modern psychosomatic medicine,providing important guidance for personalized insomnia treatment.However,its in depth mechanisms require further elucidation through subsequent high quality research.
作者 翁铭阳 卢秉久 WENG Mingyang;LU Bingjiu(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China)
机构地区 辽宁中医药大学
出处 《实用中医内科杂志》 2026年第3期62-65,共4页 Journal of Practical Traditional Chinese Internal Medicine
基金 全国名老中医药专家传承工作室建设项目(国中医药人教函[2022]75号)。
关键词 失眠 不寐 心肝同治 辨证论治 机制探讨 insomnia bumei heart liver simultaneous regulation pattern differentiation and treatment mechanism exploration
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