摘要
多囊卵巢综合征(PCOS)是青春期及育龄期女性常见的生殖内分泌代谢紊乱性疾病,近年来其临床发病率呈逐步升高且年轻化趋势。研究表明,该病发病机制主要与遗传、下丘脑-垂体-卵巢(HPO)轴功能紊乱、肠道菌群失衡、慢性炎症状态、氧化应激损伤等有关。近年来,针刺、艾灸、耳穴、穴位埋线等中医特色外治技术通过多靶点、多途径的综合调控作用,在改善PCOS患者临床症状和提高其生命质量方面展现出显著疗效。
Polycystic ovary syndrome(PCOS)is a common reproductive endocrine and metabolic disorder affecting adolescent and women of reproductive age.In recent years,its clinical incidence has shown a gradual increase and a trend toward younger onset.Studies indicate that the pathogenesis of PCOS is mainly associated with genetic factors,dysfunction of the hypothalamic-pituitary-ovarian(HPO)axis,imbalance of intestinal microbiota,chronic inflammatory status,and oxidative stress injury.In recent years,traditional Chinese medicine external therapies,including acupuncture,moxibustion,auricular therapy,and acupoint catgut embedding,have demonstrated significant efficacy in improving clinical symptoms and enhancing quality of life in patients with PCOS through multi-target and multi-pathway comprehensive regulation.
作者
亓文隆
贾志诚
李永谦
王培璇
石梦雨
杨鑫鑫
孙昕玮
郭颖
QI Wenlong;JIA Zhicheng;LI Yongqian;WANG Peixuan;SHI Mengyu;YANG Xinxin;SUN Xinwei;GUO Ying(The First Clinical College,Shandong University of Traditional Chinese Medicine,Ji'nan 250014,China;College of Traditional Chinese Medicine,Shandong University of Traditional Chinese Medicine,Ji'nan 250014,China;Center for Reproduction and Genetics,Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Ji'nan 250011,China)
出处
《世界中医药》
北大核心
2025年第23期4329-4337,共9页
World Chinese Medicine
基金
国家自然科学基金项目(82374505)
山东省自然科学基金项目(ZR2023MH219)
泰山学者青年专家项目(202211353)。
关键词
中医外治法
多囊卵巢综合征
临床疗效
作用机制
针刺
艾灸
耳穴
穴位埋线
External treatment in traditional Chinese medicine
Polycystic ovary syndrome
Clinical efficacy
Mechanism of action
Acupuncture
Moxibustion
Auricular therapy
Acupoint catgut embedding
