摘要
目的:系统整理国内疾病指南文献中的安宫牛黄丸(ANP)应用现状。方法:计算机检索PubMed、Cochrane Library、EMbase、国家知识基础设施数据库(CNKI)、中国生物医学文献数据库(CBM)、中国学术期刊数据库(CSPD),各指南数据库以及中国卫生和计划生育委员会、学术组织(如中华中医药学会、中华医学会)等官方网站。使用Excel对最终纳入的指南基本信息和ANP应用信息进行提取对比。结果:最终共纳入指南73篇。提及ANP的疾病指南发布时间近20年相对稳定,发布机构以中华中医药学会为主;循证指南31篇,大多采用文献研究、专家调查等方法编制,形成证据分级并做出推荐意见,内容涉及疾病的诊断、治疗及护理等方面;纳入指南涉及的疾病类型涉及内外妇儿等临床各科急危重症,其中内科最多(69.86%);纳入的疾病指南均提及使用ANP治疗,其中29篇(39.73%)推荐应用ANP,但是大多推荐不足。17篇(39.73%)报道了证据级别,但是质量偏低。约40%的指南推荐应用ANP,然而推荐级别不高,同时缺少高质量的循证证据。结论:疾病诊疗指南发布机构以中华中医药学会为主,近20年相对稳定。ANP应用集中于促醒退热,临床各科急危重症均有使用。
Objective:To systematically summarize the application status of Angong Niuhuang Pills(ANP)in disease guidelines in China.Methods:PubMed,Cochrane Library,EMBASE,China National Knowledge Infrastructure(CNKI),China Biology Medicine(CBM),Wanfang Data Knowledge Service Platform,guideline databases,and the official websites of the National Health and Family Planning Commission of China and academic organizations(such as the China Association of Chinese Medicine and the Chinese Medical Association)were searched.Microsoft Excel was used to extract and compare the basic information of the included guidelines and data related to the application of ANP.Results:A total of 73 guidelines were finally included.The publication of disease guidelines mentioning ANP has remained relatively stable over the past 20 years,with the China Association of Chinese Medicine being the main issuing body.Thirty-one guidelines were evidence-based,most of which were developed using literature research and expert consultation,with evidence grading and recommendation formulation,covering disease diagnosis,treatment,and nursing.The diseases involved acute and critical conditions across clinical specialties,including internal medicine,surgery,gynecology,and pediatrics,with internal medicine accounting for the highest proportion(69.86%).All included disease guidelines mentioned the use of ANP for treatment,among which 29(39.73%)recommended its application,although most recommendations were insufficient.Seventeen guidelines(39.73%)reported levels of evidence,but the overall quality was low.Approximately 40%of the guidelines recommended the use of ANP;however,the recommendation strength was low,and high-quality evidence was lacking.Conclusion:The disease diagnosis and treatment guidelines were mainly issued by the China Association of Chinese Medicine and have remained relatively stable over the past 20 years.The application of ANP is mainly concentrated on promoting resuscitation and reducing fever and is used in acute and critical conditions across various clinical specialties.
作者
孟祥然
朱雪松
李少红
曹雪
王馨
秦宇宁
何丽云
刘佳
MENG Xiangran;ZHU Xuesong;LI Shaohong;CAO Xue;WANG Xin;QIN Yuning;HE Liyun;LIU Jia(Department of Traditional Chinese Medicine,The Affiliated Wuxi People′s Hospital of Nanjing Medical University,Wuxi 214023,China;Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China;Acupuncture Clinic,Beijing Massage Hospital,Beijing 100035,China;Treatment Center of Traditional Chinese Medicine,Beijing Bo′ai Hospital,China Rehabilitation Research Center,Beijing 100068,China)
出处
《世界中医药》
北大核心
2025年第24期4452-4460,共9页
World Chinese Medicine
基金
国家重点研发计划项目(2019YFC1712200)
中国中医科学院科技创新工程项目(CI2021A00702-2)
北京市中医药科技基金项目(BJZYYB-2023-74)。
关键词
安宫牛黄丸
指南
应用现状
经典名方
疾病谱
专家共识
诊疗方案
Angong Niuhuang Pills
Guideline
Application status
Classic famous prescriptions
Disease spectrum
Expert consensus
Diagnosis and treatment plan
