摘要
目的比较2014—2023年中国与非洲疟疾流行趋势与疾病负担差异,从药物应用角度探讨防控策略。方法基于国家统计局与全球疾病负担(GBD)数据,采用描述性分析比较中国与非洲疟疾流行状况。结果中国疟疾发病率呈下降趋势,并成功消除;非洲负担持续严峻,2023年发病数超2.4亿。非洲内部负担以西非与中非较为严重。结论中国与非洲处于疟疾防控的不同阶段。以青蒿素为基础的联合疗法(ACTs)是中国成功的核心经验,而药物可及性不足与抗药性风险是非洲面临的主要挑战。中非合作应优先关注药物可及性提升与抗药性联合监测。
Objective To compare the differences in malaria epidemic trends and burden between China and Africa regions from 2014 to 2023,and to explore implications for prevention and control from the perspective of drug application.Methods Based on data from the National Bureau of Statistics of China and the Global Burden of Disease(GBD)Study,statistical analyses were performed using descriptive statistics.Results China demon-strated a significant downward trend in malaria incidence(P<0.05)and successfully achieved elimination.In contrast,Africa continued to face a severe disease burden,with reported cases exceeding 240 million in 2023.The burden within Africa was heterogeneous,with Western and Central Africa being the most severely affected.Conclusion China and Africa are at different stages of malaria prevention and control.Artemisinin-based combination therapies(ACTs)constitute the core component of China′s success,while the insufficient drug accessibility and the risk of antimalarial drug resistance remain major challenges in Africa.China-Africa cooperation should prioritize enhancing drug accessibility and establishing joint monitoring mechanisms for drug resistance.
作者
郝鸿雁
Hao Hongyan(Department of Clinical Labortory,Shanxi Second People′s Hospital,Taiyuan,Shanxi 030012,China)
出处
《中国药物与临床》
2026年第3期178-183,共6页
Chinese Remedies & Clinics
关键词
疟疾
全球疾病负担
流行趋势
青蒿素
Malaria
Global of burden disease
Epidemiological Trends
Artemisinin
