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食管淋巴上皮瘤样癌1例并文献复习

One case of lymphoepithelioma-like carcinoma of the esophagus and literature review
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摘要 食管淋巴上皮瘤样癌(LELC)是一种罕见的未分化肿瘤,临床表现缺乏特异性,诊疗中易被误诊,与其他未分化肿瘤相比,预后较好。本文报道1例患者,经多次超声内镜检查均误诊为平滑肌瘤,但因病变生长速度异常,最终行黏膜下隧道内镜肿瘤切除术,术后活检及免疫组织化学确诊为食管LELC。该病例的快速进展表现与传统生长缓慢观点不同,本文系统描述该病例的诊疗过程,并结合文献分析食管LELC特征,以提高对该疾病的认识和理解。 Lymphoepithelioma-like carcinoma(LELC)of the esophagus is a rare undifferentiated carcinoma with non-specific clinical manifestations,often leading to misdiagnosis.It generally has a better prognosis than other undifferentiated carcinomas.This article reports a case initially misdiagnosed as a leiomyoma on multiple endoscopic ultrasonography examinations.However,due to the lesion’s unusually rapid growth,the patient finally underwent submucosal tunneling endoscopic resection.The diagnosis of esophageal LELC was confirmed by postoperative biopsy and immunohistochemistry.The rapid progression observed in this case contrasts with the conventional view of its indolent nature.This paper systematically describe the diagnosis and treatment process of this patient and analyze the characteristics of esophageal LELC in combination with the literature,aiming to enhance recognition and understanding of this disease.
作者 贺晶晶 包志贤 赵越 姬瑞 HE Jingjing;BAO Zhixian;ZHAO Yue;JI Rui(The First Clinical Medical College,Lanzhou University,Gansu Province,Lanzhou730000,China;Department of Gastroenterology,the First Hospital of Lanzhou University,Gansu Province,Lanzhou730000,China)
出处 《中国医药导报》 2026年第2期193-196,F0003,共5页 China Medical Herald
基金 甘肃省自然科学基金资助项目(22JR5RA922) 中央引导地方科技发展资金项目(25ZYJA02)。
关键词 食管肿瘤 淋巴上皮瘤样癌 淋巴上皮癌 Esophageal neoplasms Lymphoepithelioma-like carcinoma Lymphoepithelial carcinoma
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