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乙型肝炎病毒相关性肝癌患者就医延迟影响因素分析

Analysis of factors influencing delays in seeking medical care among patients with hepatitis B virus-associated hepatocellular carcinoma
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摘要 目的探讨乙型肝炎病毒(HBV)相关性肝癌患者就医延迟情况及其影响因素。方法回顾性分析2024年2月至2024年12月在中山大学附属第三医院肝胆外科诊治的285例HBV相关性肝癌患者临床资料。通过问卷调查收集患者社会人口学、就医行为等资料。患者就医延迟的影响因素分析采用Logistic回归分析。结果患者就医延迟发生率为28.4%(81/285)。多因素Logistic回归分析显示,居住地(OR=0.339,P=0.005)、是否知晓乙型肝炎是肝癌高危因素(OR=0.426,P=0.022)、就医态度(OR=0.035,P<0.001)及是否服用中草药控制症状(OR=5.101,P=0.029)是就医延迟的独立影响因素。结论居住地、是否知晓乙型肝炎是肝癌高危因素、就医态度及是否服用中草药偏方是HBV相关性肝癌患者就医延迟的影响因素。建议采取针对性措施,如加强农村地区健康宣教、提高公众对乙型肝炎与肝癌关联的认知、倡导积极就医观念、规范中草药使用,以减少就医延迟,改善患者预后。 Objective To explore the delay in seeking medical care and its influencing factors among patients with hepatitis B virus(HBV)-associated hepatocellular carcinoma.Methods Clinical data of 285 HBV-associated hepatocellular carcinoma(HCC)patients who were treated in the Department of Hepatobiliary Surgery,the Third Affiliated Hospital of Sun Yat-sen University from February 2024 to December 2024 were analyzed retrospectively.A questionnaire survey was used to collect demographic,medical-seeking behavior,and other data.Logistic regression analysis was used to identify factors influencing the delay in seeking medical care.Results The incidence of delayed medical care was 28.4%(81/285).Multivariate Logistic regression analysis showed that residence(OR=0.339,P=0.005),awareness of HBV is a high-risk factor for HCC(OR=0.426,P=0.022),attitude toward seeking medical care(OR=0.035,P<0.001),and the use of traditional Chinese medicine to control symptoms(OR=5.101,P=0.029)were independent factors influencing the delay in seeking medical care.Conclusions Residence,awareness of HBV is a high-risk factor for HCC,attitude toward seeking medical care,and the use of traditional Chinese medicine are key factors influencing the delay in seeking medical care among patients with HBV-associated HCC.Targeted measures are recommended,such as strengthening health education in rural areas,increasing public awareness of the connection between HBV and HCC,advocating for proactive healthcare attitudes,and regulating the use of traditional Chinese medicine,to reduce medical care delays and improve patient prognosis.
作者 邹燕 张妮 陈奕辰 顾娇娇 ZOU Yan;ZHANG Ni;CHEN Yichen;GU Jiaojiao(Department of Hepatobiliary Surgery,the Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China;School of Nursing,Sun Yat-sen University,Guangzhou 510080,China)
出处 《新医学》 2026年第2期162-170,共9页 Journal of New Medicine
基金 广东省基础与应用基础研究基金(2023A1515010135)。
关键词 原发性肝癌 HBV相关性肝癌 乙型肝炎病毒 就医延迟 影响因素 Primary liver cancer HBV-associated hepatocellular carcinoma Hepatitis B virus Delay in seeking medical care Influencing factors
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