摘要
目的探讨男性不育症患者的抑郁、焦虑及压力情绪状态对精液质量的影响,并分析夫妻关系质量与情感性触摸行为在上述关联中的作用。方法选取2024年3月至12月在海军军医大学第一附属医院生殖医学中心接受体外受精-胚胎移植治疗的154例男性不育症患者为研究对象。采用一般资料调查表收集人口学与临床信息;使用抑郁-焦虑-压力量表、夫妻关系问卷和情感性触摸量表分别评估患者的负性情绪水平、夫妻关系质量以及情感性触摸频率。精液质量指标(包括精子活动率、前向运动率、精子浓度)数据来源于患者胚胎移植前的精液动态分析报告。结果男性不育症患者伴有抑郁、焦虑、压力情绪的比例分别为11.7%(18/154)、15.6%(24/154)和11.0%(17/154)。年龄≥33岁组不育症患者的抑郁、焦虑和压力情绪得分及精子浓度均高于年龄<33岁组,而情感性触摸得分低于年龄<33岁组(均P<0.05)。日运动时长≥60 min组不育症患者的抑郁和压力情绪得分均低于日运动时长<60 min组(均P<0.05)。相关分析显示,抑郁、焦虑及压力情绪之间两两正相关(均P<0.01),而三者均与精子活动率呈负相关(P<0.01或P<0.05);抑郁情绪与精子前向运动率呈负相关(P<0.01);夫妻情感质量与夫妻认知水平呈正相关(P<0.01),且两者均与抑郁、焦虑及压力情绪呈负相关(均P<0.01);情感性触摸频率与夫妻情感及夫妻认知水平均呈正相关(均P<0.01),但与精子浓度呈负相关(P<0.05)。分层回归分析显示,焦虑情绪与精子活动率呈负相关(t=-1.993,P=0.048),情感性触摸频率与精子浓度呈负相关(t=-2.271,P=0.025);夫妻认知水平与抑郁(t=-2.875,P=0.005)、焦虑(t=-4.186,P<0.001)、压力(t=-4.099,P<0.001)水平均呈负相关;吸烟量与焦虑(t=2.166,P=0.032)、压力(t=2.010,P=0.046)水平呈正相关;婚姻持续时长与焦虑情绪呈正相关(t=2.531,P=0.012)。结论男性不育症患者负性情绪常见,抑郁、焦虑及压力情绪与精子活动率下降相关,较高的夫妻关系质量可缓解负性情绪,情感性触摸频率关联夫妻关系与精子浓度。
Objective To investigate the impact of depression,anxiety,and stress on semen quality in male infertility patients and to analyze the role of marital relationship and affective touch behaviors in this association.Methods A total of 154 male infertility patients who underwent in vitro fertilization-embryo transfer treatment at the Reproductive Medicine Center of The First Affiliated Hospital of Naval Medical University between Mar.to Dec.2024 were enrolled.Demographic and clinical data were collected using a general information questionnaire.The depression-anxiety-stress scale,marital relationship questionnaire,and affective touch scale were used to assess negative emotion levels,marital relationship,and affective touch frequency,respectively.Semen quality parameters-including sperm motility,progressive motility,and sperm concentration-were obtained from semen dynamic analysis reports prior to embryo transfer.Results The proportions of infertility patients with depression,anxiety,and stress were 11.7%(18/154),15.6%(24/154),and 11.0%(17/154),respectively.Infertility patients aged≥33 years had higher scores for depression,anxiety,and stress,as well as higher sperm concentration,but had significantly lower score of affective touch compared to those aged<33 years(all P<0.05).Patients with daily exercise duration≥60 min had significantly lower depression and stress scores than those with<60 min(all P<0.05).Correlation analysis showed that depression,anxiety,and stress were positively correlated with each other(all P<0.01),while all 3 were negatively correlated with sperm motility(P<0.01 or P<0.05).Depression was also negatively correlated with progressive motility(P<0.01).Marital relationship and marital cognition were positively correlated with each other(P<0.01)and negatively correlated with depression,anxiety,and stress(all P<0.01).The frequency of affective touch was positively correlated with marital relationship and marital cognition(both P<0.01),but was negatively correlated with sperm concentration(P<0.05).Hierarchical regression analysis revealed that anxiety was negatively correlated with sperm motility(t=-1.993,P=0.048),and the frequency of affective touch was negatively correlated with sperm concentration(t=-2.271,P=0.025).Marital cognition was significantly negatively correlated with depression(t=-2.875,P=0.005),anxiety(t=-4.186,P<0.001),and stress(t=-4.099,P<0.001).Smoking amount was positively correlated with anxiety(t=2.166,P=0.032)and stress(t=2.010,P=0.046).Marriage duration was positively correlated with anxiety(t=2.531,P=0.012).Conclusion Negative emotions are common in male infertility patients,and depression,anxiety,and stress are associated with reduced sperm motility.Higher marital relationship can alleviate negative emotions,and the frequency of affective touch is associated with marital relationship and sperm concentration.
作者
曾文峰
张青
包俊华
汪晓冉
颜宏利
王云霞
ZENG Wenfeng;ZHANG Qing;BAO Junhua;WANG Xiaoran;YAN Hongli;WANG Yunxia(Faculty of Psychology,Naval Medical University(Second Military Medical University),Shanghai 200433,China;Reproductive Medicine Center,The First Affiliated Hospital of Naval Medical University(Second Military Medical University),Shanghai 200433,China)
出处
《海军军医大学学报》
北大核心
2026年第2期222-230,共9页
Academic Journal of Naval Medical University
关键词
不育症
负性情绪
精液质量
夫妻关系
情感性触摸
infertility
negative emotion
semen quality
marital relationship
affective touch
