摘要
周围神经手术包括周围神经切断术和神经转移术,是治疗中枢神经系统损伤导致痉挛性瘫痪的有效措施。周围神经切断术通过切断部分神经,可降低肌肉张力;周围神经-侧侧吻合术(side-to-side neurorrhaphy,STS)通过神经干开窗吻合,降低张力的同时促进功能恢复;健侧颈7神经转移术(contralateral cervical 7 nerve transposition,CC7)结合神经切断和神经转移,还能够诱发大脑可塑性;此外,初步研究提示周围神经平衡术在治疗痉挛性瘫痪中亦具有潜在应用价值。未来研究应着重于优化周围神经手术技术和评估方法,扩大临床应用,尤其是对如何提高大脑可塑性,强化功能重建进行深入探讨,以推动其进一步发展,满足更多痉挛性瘫痪患者需求。
Peripheral nerve surgery,including peripheral neurotomy and nerve transfer,is an effective treatment for spastic paralysis resulting from central nervous system injuries.Peripheral neurotomy reduces muscle tension by severing portions of nerves;side-to-side neurorrhaphy(STS)employs nerve trunk incision and sutures to decrease tone while promoting functional recovery;contralateral cervical 7 nerve transposition(CC7)combines sectioning with transposition and additionally induces brain plasticity.Furthermore,preliminary studies suggest peripheral nerve balancing holds potential for treating spastic paralysis.Future research should focus on optimization of peripheral nerve surgical techniques and evaluation methodologies,expansion clinical applications,and particularly exploration of strategies to enhance brain plasticity and strengthen functional recovery.These efforts will advance the field to better serve more patients with spastic paralysis.
作者
谢宇杰
高海峰
刘丽娜
徐静
杨德刚
高峰
陈亮
宫慧明
李军
XIE Yujie;GAO Haifeng;LIU Lina;XU Jing;YANG Degang;GAO Feng;CHEN Liang;GONG Huiming;LI Jun(Rehabilitation College,Shandong University of Chinese Medicine,Jinan 250355,China;Beijing Bo’ai Hospital,China Rehabilitation Research Center,Beijing 100068,China)
出处
《中国神经精神疾病杂志》
北大核心
2026年第1期54-59,共6页
Chinese Journal of Nervous and Mental Diseases
关键词
痉挛性瘫痪
周围神经手术
肌张力
肢体功能重建
大脑可塑性
Spastic paralysis
Peripheral nerve surgery
Muscle tonus
Limb functional reconstruction
Brain plasticity
