摘要
Dear editor,Malignant peripheral nerve sheath tumors(MPNSTs)are rare,aggressive sarcomas arising from peripheral nerves or pre-existing neurofibromas,accounting for approximately 5%10%of all soft tissue sarcomas[1].These tumors are notoriously heterogeneous:approximately 50%associated with neurofibromatosis type 1(NF1),40%occurring sporadically,and 10%linked to prior radiation exposure[2].
基金
supported by the grant:the National Key Research and Development Program of China(No.2023YFC2508500)
the National Natural Science Foundation of China(Nos.82272951 and 82272953).
