摘要
目的:探讨社区中老年人估计脉搏波速度动态变化轨迹及其与心血管疾病的关系。方法:基于中国健康与养老追踪调查(CHARLS)的队列数据,收集人群一般资料及实验室指标。采用群组轨迹模型(GBTM)构建社区中老年人估计脉搏波速度动态变化的异质性轨迹,应用Logistic回归分析探讨估计脉搏波速度动态变化轨迹与心血管疾病的关系。结果:共5 933名参与者纳入分析,其中发生心血管疾病1 112例(18.7%)。群组轨迹模型分析显示,存在4种估计脉搏波速度变化轨迹:低水平稳定组(30.0%)、中水平上升组(39.6%)、上升后平稳组(23.0%)和高水平上升组(7.4%)。Logistic回归分析显示,校正混杂因素后,相对于低水平稳定组,中水平上升组、上升后平稳组和高水平上升组心血管疾病的发生风险明显增加。结论:社区中老年人的估计脉搏波速度变化轨迹存在群体异质性,较高的估计脉搏波速度轨迹与心血管疾病的发生相关。提示医务人员应重视中老年人的估计脉搏波速度变化,并根据不同轨迹制定对应干预策略。
Objective:To explore the dynamic trajectory of estimated pulse wave velocity in middle-aged and elderly people and its relationship with cardiovascular diseases.Methods:Based on the population cohort data from the China health and retirement longitudinal study(CHARLS),general information and laboratory indicators of the population were collected.The group-based trajectory model(GBTM)was used to construct the heterogeneous trajectories of the estimated pulse wave velocity dynamics in the community among the elderly.Logistic regression analysis was applied to explore the relationship between the estimated pulse wave velocity dynamic trajectory and cardiovascular diseases.Results:A total of 5933 participants were included in the analysis,among whom 1112 cases(18.7%)developed cardiovascular diseases.The GBTM analysis revealed four estimated trajectories of pulse wave velocity changes:the low-level stable group(30.0%),the medium-level ascending group(39.6%),the ascending and stable group(23.0%),and the high-level ascending group(7.4%).Logistic regression analysis showed that,after adjusting for confounding factors,compared with the low-level stable group,the risk of cardiovascular diseases significantly increased in the medium-level ascending group,the ascending and stable group,and the high-level ascending group.Conclusions:The estimated pulse wave velocity trajectories of the elderly in the community showed population heterogeneity.The higher estimated pulse wave velocity trajectories was correlated with the occurrence of cardiovascular diseases.It is suggested that medical staff should pay attention to the changes in the estimated pulse wave velocity of the elderly and formulate corresponding intervention strategies based on different trajectories.
作者
黄明亮
马秋平
HUANG Mingliang;MA Qiuping(Guangxi University of Chinese Medicine,Guangxi 530200 China)
出处
《护理研究》
北大核心
2026年第4期542-548,共7页
Chinese Nursing Research
基金
广西中医药大学高层次人才队伍建设三年行动计划项目(老年健康照护创新研究团队),编号:04B24009A0。
关键词
中老年人
估计脉搏波速度
心血管疾病
群组轨迹模型
middle-aged and elderly people
estimated pulse wave velocity
cardiovascular diseases
group-based trajectory model
