摘要
目的:分析山东省梅毒流行病学特征,为预防和控制梅毒提供理论依据。方法:运用SPSS、Geoda和ArcGIS等工具,基于2014-2024年山东省梅毒数据对其时间、空间分布进行分析。结果:山东省梅毒总体发病率呈现上升趋势(EAPC=3.08,P<0.01),其中隐性梅毒增长最快(EAPC=8.58,P<0.01)。相较而言,一期、二期、三期及胎传梅毒发病率均呈不同程度下降,其中胎传阶段梅毒下降最明显(EAPC=-15.83,P<0.01)。梅毒在全省呈现显著的空间聚集特征,且聚集格局随时间演变发生变化,高发区早期集中在东部沿海县/区,近年逐步向中部、西部内陆地区扩展。结论:山东省梅毒疫情呈现总体上升、隐性梅毒主导、高发区由东部向西部转移的多重特征。防控策略应当从“被动发现”向“主动筛查”转变,从“全省一体”向“重点聚焦”调整。
Objective:To analyze the epidemiological characteristics of syphilis in Shandong Province from 2014 to 2024,providing a theoretical basis for prevention and control strategies.Methods:The temporal and spatial distribution characteristics of syphilis data in Shandong Province from 2014 to 2024 was analyzed in SPSS,Geoda and ArcGIS.Results:The reported incidence of syphilis showed an upward trend(EAPC=3.08,P<0.01),with latent syphilis exhibiting the fastest growth(EAPC=8.58,P<0.01).In comparison,the reported incidences of primary,secondary,tertiary and congenital syphilis declined to varying degrees,among which congenital syphilis demonstrated the most significant decrease(EAPC=-15.83,P<0.01).Spatially,syphilis in Shandong exhibited significant clustering patterns and has changed over time,initially the high-incidence areas concentrated in eastern coastal counties/districts and have gradually expanded to central and western regions in recent years.Conclusion:The syphilis epidemic in Shandong Province presents multiple characteristics such as an overall increase,latent dominance,and the shift of high-incidence areas from east to west.Strategiesof syphilis prevention and control should be transformed from passive detection to active screening and a uniform provincial approach should be shifted to targeted interventions in key regions.
作者
范高远
李珍
暴芳芳
初同胜
黄娜
郑荣涛
侯建玲
田洪青
刘殿昌
刘红
张福仁
FAN Gaoyuan;LI Zhen;BAO Fangfang;CHU Tongsheng;HUANG Na;ZHENG Rongtao;HOU Jianling;TIAN Hongqing;LIU Dianchang;LIU Hong;ZHANG Furen(Dermatology Hospital of Shandong First Medical University,Jinan 250022,China;Shandong Provincial Institute of Dermatology and Venereology,Shandong Academy of Medical Sciences,Jinan 250022,China)
出处
《中国麻风皮肤病杂志》
2026年第2期92-96,共5页
China Journal of Leprosy and Skin Diseases
关键词
梅毒
流行特征
时空分布
syphilis
epidemiological characteristics
spatiotemporal distribution
