摘要
目的探讨透析龄对腹膜透析(PD)患者胃肠道症状及其生活质量的影响,并分析PD患者胃肠道健康的相关影响因素。方法通过发放胃肠道生活质量量表(GIQLI)电子问卷进行调查,记录患者的人口学资料和临床数据,将患者分为短透龄组(透析龄≤3年)和长透龄组(透析龄>3年),进行组间得分比较,使用线性回归模型分析胃肠道健康的影响因素。结果共回收问卷154份,其中长透龄组(n=84)与短透龄组(n=70)相比,GIQLI总分、胃肠道症状得分、身体功能得分、社会功能得分、治疗影响得分均显著降低(P<0.05);透析龄、腹膜Ccr、血尿素氮是GIQLI总分及其胃肠道症状得分的独立危险因素(P<0.05)。结论透析龄、腹膜Ccr及血尿素氮的增加可导致PD患者的胃肠道生活质量及胃肠道症状受损。
Objective To investigate the impact of dialysis age on gastrointestinal(GI)symptoms and quality of life in peritoneal dialysis(PD)patients,and identify the factors influencing GI health in PD patients.Methods An electronic Gastrointestinal Quality of Life Index(GIQLI)questionnaire was distributed for investigation.Demographic and clinical data of patients were recorded.The patients were divided into a short-dialysis age group(dialysis age≤3 years)and a long-dialysis age group(dialysis age>3 years).Scores were compared between the two groups.Linear regression model was used to analyze the influencing factors of GI health.Results A total of 154 questionnaires were collected.Compared with the short-dialysis age group(n=70),the long-dialysis age group(n=84)had significantly lower total GIQLI scores,gastrointestinal symptom scores,physical function scores,social function scores and treatment impact scores(P<0.05).Dialysis age,peritoneal creatinine clearance and blood urea nitrogen were independent risk factors for total GIQLI scores and GI symptom scores.Conclusions Increased dialysis age,peritoneal creatinine clearance and blood urea nitrogen can lead to impaired gastrointestinal quality of life and gastrointestinal symptoms in PD patients.
作者
杨仁静
谭歆怡
李艳
周勤
刘文淑
李彭莉
陈瑾
YANG Ren-jing;TAN Xin-yi;LI Yan;ZHOU Qin;LIU Wen-shu;LI Peng-li;CHEN Jin(Department of Nephrology,The Affiliated Hospital of Southwest Medical University,Luzhou 646000,China;Department of Nephrology,Sichuan Academy of Medical Sciences&Sichuan Provincial People's Hospital(Affiliated Hospital of University of Electronic Science and Technology of China),Chengdu 610072,China)
出处
《实用医院临床杂志》
2026年第1期115-121,共7页
Practical Journal of Clinical Medicine
基金
四川省中医药管理局课题(编号:2024MS520)。
关键词
腹膜透析
胃肠道生活质量量表
胃肠道症状
透析龄
Peritoneal dialysis
Gastrointestinal quality of life index
Gastrointestinal symptoms
Dialysis age
