摘要
随着水产需求品的日益增加,化学药剂和抗生素类药物带来的多种环境污染和病原体耐药性增加等问题逐渐凸显,迫切需要寻找副作用较小的中草药作为替代药物。大黄素作为一种危害低、资源丰富、毒副作用小的蒽醌类中草药提取物,受到国内外研究者的广泛关注,逐渐成为新型鱼药的重点研究方向。本文从大黄素对水产动物抗氧化应激、抗病原体、调节免疫、改善肠道功能以及保护肝脏细胞的多方面,阐述了大黄素在国内外水产养殖中的研究进展,为大黄素成为水产养殖中新型添加剂的应用发展提供参考。
With the increasing demand for aquatic products,issues such as various environmental pollution caused by chemical agents and antibiotics,as well as the growing resistance of pathogens,have become increasingly prominent.There is an urgent need to explore Chinese herbal medicines with fewer side effects as alternative treatments.Emodin,an anthraquinone-type extract from Chinese herbs medicine,abundant resources,and minimal toxicity and side effects,has garnered widespread attention from researchers both domestically and internationally.It is gradually emerging as a key research direction for novel fish medicines.This article reviews the progress of research on emodin in aquaculture worldwide,focusing on its multiple effects,including antioxidative stress,pathogen resistance,immune regulation,improvement of intestinal function,and protection of liver cells in aquatic animals.It aims to provide a reference for the application and development of emodin as a novel additive in aquaculture.
作者
李佩泽
余贵海
窦勇
李瑞丽
高金伟
张丹
周文礼
邵蓬
LI Peize;YU Guihai;DOU Yong;LI Ruili;GAO Jinwei;ZHANG Dan;ZHOU Wenli;SHAO Peng(College of Fisheries,Tianjin Key Laboratory of Aquatic Ecology and Aquaculture,Tianjin Agricultural University,Tianjin 300384,China)
基金
国家重点研发计划课题(2024YFD2401803)
天津市科技计划项目(25ZYCGSN00800,25YDTPJC00340)
天开高教科创园企业研发专项项目(23YFZXYC00017)。
关键词
大黄素
蒽醌类化合物
水产动物
作用机理
影响因素
emodin
anthraquinone compounds
aquatic animals
mechanism of action
influencing factors
