摘要
目的研究间歇性θ短阵脉冲刺激(iTBS)与认知训练联合应用对卒中后认知障碍(PSCI)患者认知和神经功能的改善作用。方法纳入2022年7月—2024年7月期间在漯河市中心医院收治的80例PSCI患者,并按随机原则分为40例观察组与40例对照组。观察组接受iTBS联合认知训练,对照组接受常规治疗加认知训练。比较两组治疗前后在认知功能、日常记忆功能、日常生活活动能力、认知灵活性及神经功能等方面的变化。结果治疗4周后,两组患者的认知功能均有改善,与仅接受认知训练的对照组相比,观察组的认知功能、日常记忆功能和日常生活活动能力评分显著升高(P<0.05),认知灵活性、神经功能显著改善(P<0.05)。结论iTBS联合认知训练能够显著改善PSCI患者的认知功能和神经功能。
Objective To investigate the effect of intermittentθburst stimulation(iTBS)combined with cognitive training in improving the cognitive and neurological functions of patients with post-stroke cognitive impairment(PSCI).Methods A total of 80 patients with PSCI who were admitted to our hospital from July 2022 to July 2024 were enrolled in the study,and they were randomly divided into observation group and control group,with 40 patients in each group.The patients in the observation group received iTBS combined with cognitive training,while those in the control group received conventional treatment combined with cognitive training.The two groups were compared in terms of the changes in cognitive function,daily memory function,activities of daily living,cognitive flexibility,and neurological function after treatment.Results After 4 weeks of treatment,both groups had improvement in cognitive function,and compared with the control group receiving cognitive training alone,the observation group had significant increases in the scores of cognitive function,daily memory function,and activities of daily living(P<0.05),with significant improvements in cognitive flexibility and neurological function(P<0.05).Conclusion The combination of iTBS and cognitive training can significantly improve cognitive and neurological functions in patients with PSCI.
作者
程娟娟
李陶威
邢娜
CHENG Juanjuan;LI Taowei;XING Na(Department of Rehabilitation Medicine,Luohe Central Hospital,Luohe 462000,China;Department of Rehabilitation Medicine,The First Affiliated Hospital of Zhengzhou University,Zhenzhou 450052,China)
出处
《中风与神经疾病杂志》
2026年第1期65-69,共5页
Journal of Apoplexy and Nervous Diseases
基金
国家自然科学基金资助项目(82372510)。
关键词
脑卒中后认知障碍
间歇性θ短阵脉冲刺激
认知训练
认知功能
Post-stroke cognitive impairment
Intermittentθburst stimulation
Cognitive training
Cognitive function
