摘要
文章集中探讨结核性胸腔积液诊断中,结核感染T细胞斑点试验(T-SPOT.TB)、结核分枝杆菌核酸恒温扩增检测(SAT)、腺苷脱氨酶(ADA)联合运用的应用价值。选取60例不明原因胸腔积液患者作为研究对象,采集胸腔积液,实施T-SPOT.TB、SAT、ADA检测,以指南标准为金标准,计算诊断效能。金标准下确诊结核性胸腔积液患者38例,阳性检出率63.33%。T-SPOT.TB、ADA阳性检出率均低于金标准(P<0.05);SAT、联合检测阳性检出率与金标准检出率比较无差异(P>0.05)。T-SPOT.TB、SAT、ADA联合检测的诊断敏感度、特异度、阳性预测值、阴性预测值均高于单一检测(P<0.05)。在结核性胸腔积液诊断中,T-SPOT.TB、SAT、ADA联合检测具有较高的检出准确性和敏感度、特异度,值得推广。
This article explored the practical value of the combined testing of T-SPOT.TB,SAT,and ADA in the diagnosis of tuberculous pleural effusion.Sixty patients with unexplained pleural effusion were selected as the research subjects.The pleural effusion was collected and tested using T-SPOT.TB,SAT,and ADA.The diagnostic efficacy was calculated based on the gold standard of guideline standards.38 patients were diagnosed with tuberculous pleural effusion using the gold standard,with a positive detection rate of 63.33%.The positive detection rates of T-SPOT.TB and ADA were both lower than that of the gold standard(P<0.05).The positive detection rates of SAT and the combined detection showed no statistically significant difference compared to that of the gold standard(P>0.05).The diagnostic sensitivity,specificity,positive predictive value,and negative predictive value of the combined detection of T-SPOT.TB,SAT,and ADA were higher than those of single testing(P<0.05).In the diagnosis of tuberculous pleural effusion,the combined detection of T-SPOT.TB,SAT,and ADA can achieve high detection accuracy,sensitivity,and specificity,and is worthy of promotion.
作者
张伟
ZHANG Wei(Gansu Mediacl College,Pingliang 744000,China)
出处
《工业微生物》
2025年第6期10-12,共3页
Industrial Microbiology
