摘要
目的探讨在三维计算机断层扫描支气管血管成像(3D-CTBA)辅助下,使用单孔胸腔镜下肺叶切除术治疗早期非小细胞肺癌(NSCLC)患者的临床效果。方法选取徐州市铜山区中医院2022年3月至2025年3月收治的60例早期NSCLC患者作为研究对象,通过随机数字表法分为3D-CTBA组(n=30,采用3D-CTBA辅助下单孔胸腔镜下肺叶切除术治疗)和对照组(n=30,采用常规单孔胸腔镜下肺叶切除术治疗),比较两组的近期临床效果、手术与康复相关指标、呼吸功能、并发症发生情况。结果两组近期临床总有效率、淋巴结清扫数量、并发症总发生率比较,差异无统计学意义(P>0.05)。3D-CTBA组手术时间、住院时间短于对照组,术中出血量、术后胸腔引流量少于对照组(P<0.05)。与术前比较,两组术后1周呼吸功能各项指标水平均下降,但3D-CTBA组用力肺活量(FVC)、第1秒用力呼气容积(FEV1)、最大通气量(MVV)水平均高于对照组(P<0.05)。结论采用常规单孔胸腔镜下肺叶切除术与3D-CTBA辅助下单孔胸腔镜下肺叶切除术治疗早期NSCLC患者的疗效和安全性相当,但3D-CTBA辅助下单孔胸腔镜下肺叶切除术能更好地控制术中出血、缩短手术与住院时间,并促进术后呼吸功能恢复。
Objective To investigate the clinical effect of single-hole thoracoscopic lobectomy assisted by three-dimensional computed tomography bronchial angiography(3D-CTBA)in the treatment of patients with early non-small cell lung cancer(NSCLC).Methods A total of 60 patients with early NSCLC admitted to Xuzhou Tongshan Hospital of Traditional Chinese Medicine from March 2022 to March 2025 were selected as the research subjects.They were divided into 3D-CTBA group(n=30,treated with 3D-CTBA-assisted single-hole thoracoscopic lobectomy)and control group(n=30,treated with conventional single-hole thoracoscopic lobectomy)by random number table method.The short-term clinical effects,surgical and rehabilitation-related indicators,respiratory function,and occurrence of complications were compared between the two groups.Results There were no statistical differences in the total clinical effective rate,the number of dissected lymph nodes and the total incidence rate of complications between the two groups(P>0.05).The surgical time and hospitalization time of the 3D-CTBA group were shorter than those of the control group,and the intraoperative blood loss volume and postoperative thoracic drainage volume were less than those of the control group(P<0.05).Compared with those before surgery,the levels of respiratory function indexes in the two groups decreased at 1 week after surgery,but the levels of forced vital capacity(FVC),forced expiratory volume in 1 second(FEV1)and maximum ventilation volume(MVV)in the 3D-CTBA group were higher than those in the control group(P<0.05).Conclusion The efficacy and safety of conventional single-hole thoracoscopic lobectomy and 3D-CTBA-assisted single-hole thoracoscopic lobectomy in the treatment of early NSCLC patients are comparable,but 3D-CTBA-assisted single-hole thoracoscopic lobectomy can better control intraoperative blood loss,shorten surgical time and hospitalization time,and promote postoperative respiratory function recovery.
作者
张广智
张运修
ZHANG Guangzhi;ZHANG Yunxiu(Department of Thoracic Surgery,Xuzhou Tongshan District Hospital of Traditional Chinese Medicine,Xuzhou,Jiangsu 221000,China)
出处
《医师在线》
2026年第1期41-45,共5页
Journal of Doctors Online
关键词
三维计算机断层扫描支气管血管成像
肺叶切除术
单孔胸腔镜
非小细胞肺癌
呼吸功能
效果
Three-dimensional computed tomography bronchial angiography
Lobectomy
Single-hole thoracoscopy
Non-small cell lung cancer
Respiratory function
Effect
