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三甲医院科研人员人类遗传资源认知现状调查分析

Investigation and analysis of the cognition of human genetic resources among researchers in a tertiary hospital
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摘要 目的探讨某三甲医院科研人员对人类遗传资源的认知和需求,为提升科研人员相关素养、优化医院人类遗传资源管理体系建设提供依据。方法通过问卷调查,对2021-2023年间主持纵向科研项目或以第一/通讯作者发表SCI论文的325位科研人员进行调研,比较不同特征科研人员在人类遗传资源认知得分及培训参与情况上的差异。结果科研人员对人类遗传资源相关知识的总体知晓率均低于60%,认知平均得分为51.68分。性别、年龄、学历、职称、岗位、职务、是否担任研究生导师、主持或参与科研项目数量,以及科研活动中是否涉及人类遗传资源等因素均显著影响认知得分(P<0.05)。接受培训后,科研人员的认知得分显著提升(P<0.001),且科研活动中涉及人类遗传资源的科研人员参与培训的比例更高(P=0.004)。83.08%的科研人员认为有必要接受相关培训,线上授课和案例分析是最受欢迎的培训形式和内容。结论样本医院科研人员对人类遗传资源的认知水平仍有待提高,应以法律法规为准则、完善人类遗传资源管理制度,以中层干部为桥梁、强化科研人员人类遗传资源培训,以科研管理部门为基石、优化全流程管理,以构建系统化、规范化的人类遗传资源管理和监督体系,全面提升科研人员人类遗传资源素养,为医学研究的可持续发展提供保障。 Objective:To explore the cognition and demand of human genetic resources of researchers in a tertiary hospital,and provide a reference for improving the scientific literacy of researchers and optimizing the construction of human genetic resources management system in the hospital.Methods:A questionnaire survey was conducted on 325 researchers who led longitudinal research projects or published SCI papers as first/corresponding authors from 2021-2023 to compare the differences in human genetic resources cognition scores and training participation among researchers with different characteristics.Results:The overall awareness rate of human genetic resources cognition was lower than 60%,and the average cognitive score was 51.68.Gender,age,educational background,professional title,post,position,postgraduate tutor,the numbers of scientific research projects presided over or participated in,and whether human genetic resources were involved in scientific research activities significantly affected cognitive scores(P<0.05).After receiving the training,the cognitive scores of researchers were significantly improved(P<0.001),and the proportion of researchers involved in human genetic resources in scientific research activities was higher(P=0.004).About 83.08%of researchers believed that it was necessary to receive relevant training,and online teaching and case analysis were the most popular forms and contents of training.Conclusions:The cognition of scientific researchers in the sample hospital regarding human genetic resources needs to be enhanced.Through take laws and regulations as the guideline to improve the management system,take middle-level cadres as the bridge to strengthen the training for scientific researchers,and take scientific research management department as the cornerstone to optimize the whole process management,hospitals should build a systematic and standardized human genetic resources management and supervision system,comprehensively improve the human genetic resources literacy of scientific researchers,and ensure the sustainable development of medical research.
作者 蔡立 张箴波 陈伟 梁爱斌 Cai Li;Zhang Zhenbo;Chen Wei;Liang Aibin(Tongji Hospital,School of Medicine,Tongji University,Shanghai 200065,China)
出处 《中华医学科研管理杂志》 2025年第6期526-532,共7页 Chinese Journal of Medical Science Research Management
基金 2022年度上海市卫生健康委员会政策研究自选课题(2022HP70)。
关键词 三甲医院 科研人员 人类遗传资源 认知 Tertiary hospital Researchers Human genetic resources Cognition
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