摘要
目的分析2018—2024年辽宁省非免疫规划(non-national immunization program,nNIP)疫苗使用情况,对全省nNIP疫苗接种现状进行评估,为制定公共卫生政策和优化疫苗接种策略提供科学依据。方法通过“中国免疫规划信息管理系统”和“辽宁省免疫规划综合信息平台-预防接种信息系统”提取2018—2022年以及2023—2024年nNIP疫苗接种数据,其中包括nNIP疫苗替代记录。利用SPSS 13.0软件进行Pearson相关系数矩阵分析,并采用描述性分析方法对数据进行综合分析。结果2018—2024年辽宁省nNIP疫苗共接种25726024剂次,人均接种剂次为866剂次/万人,nNIP疫苗人均接种剂次、占所有疫苗接种总剂次比例均为逐年递增趋势。使用量居前3位的nNIP疫苗品种为人用狂犬病疫苗(rabies vaccine for human use,Rab)、流感疫苗(influenza vaccine,InfV)、水痘减毒活疫苗(varicella attenuated live vaccine,VarV)。在NIP中,替代率最高的为脊髓灰质炎疫苗(poliomyelitis vaccine,PV)(30.40%),其次为甲型肝炎减毒活疫苗(hepayitis A attenuated live vaccine,HepA-L)(29.08%)、无细胞百白破联合疫苗(diphtheria,tetanus and acellular pertussis combined vaccine,DTaP)(16.37%)。结论nNIP疫苗在公共卫生中的重要性日益凸显,作为预防接种的重要组成部分,需进一步加强监测质量;nNIP疫苗能够弥补NIP疫苗覆盖的不足,还可在一些NIP疫苗供应暂时短缺时发挥重要作用,在优化NIP疫苗的供应及分配的基础上提高nNIP疫苗接种水平,可有效防控疫苗可预防传染病的流行。
Objective To analyze the use of non-national immunization program(nNIP)vaccines in Liaoning Province from 2018 to 2024,evaluate the current situation of nNIP vaccination in Liaoning Province,and to provide scientific basis for formulating public health policies and optimizing vaccination strategies.Methods The nNIP vaccination data from 2018 to 2022 and 2023 to 2024 were extracted through"China Immunization Program Information Management System"and"Liaoning Province Immunization Program Comprehensive Information Platform-Vaccination Information System",including nNIP vaccine replacement records.Pearson correlation coefficient matrix analysis was performed using SPSS 13.0 software,and descriptive analysis method was used to comprehensively analyze the data.Results From 2018 to 2024,a total of 25726024 doses of nNIP vaccines were administered in Liaoning Province,with per capita dose of 866 doses per 10000 people.The per capita doses of nNIP vaccine and the proportion in total doses of all vaccines were increasing year by year.The top three nNIP vaccine varieties used were rabies vaccine for human use(Rab),influenza vaccine(InfV)and varicella attenuated live vaccine(VarV).Among the NIP,poliomyelitis vaccine(PV)showed the highest substitution rate(30.40%),followed by hepayitis A attenuated live vaccine(HepA-L)(29.08%)and diphtheria,tetanus and acellular pertussis combined vaccine(DTaP)(16.37%).Conclusion The importance of nNIP vaccines in public health has become increasingly prominent.As an important part of vaccination,the quality of surveillance needs to be further strengthened.The nNIP vaccines can make up for the lack of NIP vaccine coverage,and can also play an important role when some NIP vaccines are temporarily in short supply.On the basis of optimizing the supply and distribution of NIP vaccines,increasing the level of nNIP vaccination can effectively prevent and control the epidemic of vaccine-preventable infectious diseases.
作者
段亚彤
王燕
李萌
方兴
DUAN Yatong;WANG Yan;LI Meng;FANG Xing(Liaoning Provincial Center for Disease Control and Prevention,Shenyang 110006,Liaoning Province,China)
出处
《中国生物制品学杂志》
2025年第12期1438-1444,共7页
Chinese Journal of Biologicals
基金
辽宁省科学技术计划面上项目(2021-MS-360)。
关键词
非免疫规划疫苗
接种情况
监测质量
Non-national immunization program(nNIP)vaccines
Vaccination status
Monitoring quality
