摘要
目的探究正压排痰机联合经鼻高流量氧疗治疗肺部感染合并肺不张的价值。方法研究对象为62例肺部感染合并肺不张患者,采用随机数字表分组法分成对照组和观察组,各31例。对照组使用正压排痰机治疗,观察组使用正压排痰机联合经鼻高流量氧疗治疗。对比两组患者临床症状消失时间,血气指标[动脉血氧分压(PaO_(2))、动脉血二氧化碳分压(PaCO_(2))及血氧饱和度(SaO_(2))],临床疗效,不同时间段排痰量。结果观察组发绀、肺部啰音及气促消失时间分别为(0.47±0.13)、(4.85±1.02)、(5.22±0.93)d,均短于对照组的(0.92±0.27)、(7.14±1.68)、(7.78±1.46)d(P<0.05)。观察组PaO_(2)(75.52±6.29)mm Hg(1 mm Hg=0.133 kPa)及SaO_(2)(94.39±3.82)%相比于对照组的(68.84±5.26)mm Hg、(89.61±5.17)%更高,PaCO_(2)(46.81±4.92)mm Hg相比于对照组的(52.76±5.85)mm Hg更低(P<0.05)。观察组取得的临床总有效率(96.77%)相比于对照组(74.19%)更高(P<0.05)。治疗3、7 d,两组排痰量均较治疗前增加,且观察组排痰量(35.65±3.42)、(41.02±4.25)ml比对照组的(30.23±3.22)、(35.22±4.69)ml更多(P<0.05)。结论肺部感染合并肺不张患者采用正压排痰机联合经鼻高流量氧疗治疗可快速改善患者临床症状和血气指标,提升临床疗效及排痰量,值得进一步推广和应用。
Objective To explore the value of positive pressure sputum ejection machine combined with high flow nasal cannula oxygen therapy in the treatment of pulmonary infection complicated with atelectasis.Methods The study subjects were 62 patients with pulmonary infection complicated with atelectasis.They were divided into the control group and the observation group using a random number grouping method,each with 31 cases.The control group was treated with a positive pressure sputum ejection machine,while the observation group was treated with a positive pressure sputum ejection machine combined with high flow nasal cannula oxygen therapy.The clinical symptom disappearance time,blood gas indicators[arterial partial pressure of oxygen(PaO_(2)),arterial partial pressure of carbon dioxide(PaCO_(2)),and oxygen saturation(SaO_(2))],clinical efficacy,and sputum output at different time points of the two groups were compared.Results The disappearance time of symptoms such as cyanosis,lung rales,and shortness of breath in the observation group were(0.47±0.13),(4.85±1.02),and(5.22±0.93)d,which were shorter than those in the control group[(0.92±0.27),(7.14±1.68),and(7.78±1.46)d](P<0.05).The observation group had PaO_(2) of(75.52±6.29)mm Hg(1 mm Hg=0.133 kPa)and SaO_(2) of(94.39±3.82)%,which were higher than those in the control group[(68.84±5.26)mm Hg and(89.61±5.17)%];PaCO_(2)(46.81±4.92)mm Hg was lower than the control group's(52.76±5.85)mm Hg(P<0.05).The clinical overall response rate achieved in the observation group(96.77%)was higher than that in the control group(74.19%)(P<0.05).After 3 and 7 d of treatment,the sputum output increased in both groups compared to pretreatment levels.Moreover,the sputum output in the observation group were(35.65±3.42)and(41.02±4.25)ml,which were significantly higher than those in the control group[(30.23±3.22)and(35.22±4.69)ml](P<0.05).Conclusion The combination of positive pressure sputum machine and high flow nasal cannula oxygen therapy can quickly improve clinical symptoms,blood gas indicators,clinical efficacy,and sputum output in patients with pulmonary infection complicated with atelectasis.It is worthy of further promotion and application.
作者
葛德芹
GE De-qin(Yancheng Dafeng District People's Hospital,Yancheng 224100,China)
出处
《中国实用医药》
2026年第4期35-37,共3页
China Practical Medicine
关键词
经鼻高流量氧疗
正压排痰机
肺部感染
肺不张
High-flow nasal cannula oxygen therapy
Positive pressure phlegm ejection machine
Pulmonary infection
Atelectasis
