摘要
目的 探讨支气管镜下肺泡灌洗联合甲泼尼龙治疗儿童重症肺炎支原体肺炎(MPP)的临床效果。方法 94例儿童重症MPP患者随机分为两组,均给予基础治疗。对照组给予阿奇霉素治疗,观察组给予支气管镜下肺泡灌洗联合甲泼尼龙治疗。对两组的临床疗效、症状缓解时间、炎性指标及不良反应进行对比分析。结果 观察组的治疗效果优于对照组(P<0.05)。观察组的发热缓解时间、咳嗽缓解时间、喘息缓解时间短于对照组(P<0.05)。治疗7 d后,观察组的PCT、 IL-6、 CRP水平低于对照组(P<0.05)。两组治疗过程中的不良反应发生率比较差异不显著(P >0.05)。结论 支气管镜下肺泡灌洗联合甲泼尼龙治疗儿童重症MPP的效果较好,可加快患儿症状缓解,降低炎性指标,且安全性较高。
Objective To investigate the clinical efficacy of bronchoscopic alveolar lavage combined with methylprednisolone in the treatment of severe Mycoplasma pneumoniae pneumonia(MPP)in children.Methods 94 children with severe MPP were randomly divided into two groups,both receiving basic treatment.The control group was treated with azithromycin,while the observation group was treated with bronchoscopic alveolar lavage combined with methylprednisolone.The clinical efficacy,symptom relief time,inflammatory indicators,and adverse reactions were compared between two groups.Results The treatment effect of the observation group was better than that of the control group(P<0.05).The relief times of fever,cough and wheezing in the observation group were shorter than those in the control group(P<0.05).After 7 d of treatment,the levels of PCT,IL-6,and CRP in the observation group were lower than those in the control group(P<0.05).No significant difference showed in the incidence of adverse reactions during treatment between the two groups(P>0.05).Conclusions Bronchoscopic bronchoalveolar lavage combined with methylprednisolone in the treatment of children with severe MPP has better effect,which can accelerate symptom relief of children,and reduce inflammatory indicators,with higher safety.
作者
郑芳
伍晓莉
ZHENG Fang;WU Xiaoli(Department of Pediatrics,Sanming First Hospital,Sanming 365000,China)
出处
《临床医学工程》
2025年第12期1399-1401,共3页
Clinical Medicine & Engineering
关键词
儿童
重症肺炎支原体肺炎
支气管镜下肺泡灌洗
甲泼尼龙
Children
Severe Mycoplasma pneumoniae pneumonia
Bronchoscopic alveolar lavage
Methylprednisolone
