摘要
目的探讨广州某医院就诊人群粪便寄生虫感染的流行病学特征,尤其是华支睾吸虫感染现状,为寄生虫病防控提供数据支持。方法回顾性分析2024年中山大学附属第一医院76672名患者共85567份粪便常规检查数据,采用自动数字化粪便分析仪(KEYU KU-F40)进行初筛,并通过LIS系统提取患者匿名人口学信息(性别、年龄、居住地区)进行分析。结果672例阳性病例中,以华支睾吸虫为主(595例,88.5%),男性患者占83.4%,女性患者占16.6%;其他寄生虫:人芽囊原虫40例、蓝氏贾第鞭毛虫16例、粪类圆线虫13例、钩虫3例、鞭虫2例,日本血吸虫、肺吸虫、蛲虫各1例。73.2%(436/595)的华支睾吸虫患者年龄在50岁以上,主要的基础疾病为糖尿病(100例)、高血压(68例)、肝癌(44例)、胆道疾病(43例)。华支睾吸虫感染患者居住地主要分布在广州番禺区(12.4%)、越秀区(11.9%),佛山市顺德区(11.4%)、南海区(6.4%)。这4个区感染总数占41.7%。结论华支睾吸虫为主要感染的寄生虫,以50岁以上的男性居多,主要居住在广州的越秀和番禺区,佛山的南海和顺德区。建议制定适当的策略,以这些人群为重点,更好地实现寄生虫防控的目的。
Objective To investigate the epidemiological characteristics of fecal parasitic infections among patients attending a hospital in Guangzhou,specifically Clonorchis sinensis,and provide data support for parasitic disease prevention and control.Methods A retrospective analysis was conducted of 85567 routine stool examinations from 76672 patients at the First Affiliated Hospital of Sun Yat⁃sen University in 2024.Screening was performed using an automated digital stool analyzer(KEYU KU⁃F40).Anonymous demographic information(gender,age,and region of residence)was extracted and analyzed using the Lisboa Information System(LIS).Results Among 672 positive cases,Clonorchis sinensis predominated(595 cases,88.5%),with males accounting for 83.4%and females for 16.6%.Other parasites included Blastocystis hominis(40 cases),Giardia lamblia(16 cases),Strongyloides stercoralis(13 cases),hookworms(3 cases),and whipworms(2 cases).Schistosoma japonicum,Paragonimus solium,and Enterovilium vermicularis were also detected in 1 case each.73.2%(436/595)of patients with Clonorchis sinensis were over 50 years old.Major underlying medical conditions included diabetes(100 cases),hypertension(68 cases),liver cancer(44 cases),and biliary tract disease(43 cases).Patients infected with Clonorchis sinensis primarily resided in the high⁃endemic areas of Guangzhou's Panyu district(12.4%),Yuexiu district(11.9%),Foshan's Shunde district(11.4%),and Nanhai district(6.4%).These four districts accounted for 41.7%of the total infections.Conclusions Among patients attending our hospital,Clonorchis sinensis was the primary parasite infecting them.The majority of patients were males over 50 years old,primarily residing in Yuexiu and Panyu districts of Guangzhou and Nanhai and Shunde districts of Foshan.Appropriate parasite control strategies should be developed to prioritize these populations as the major target.
作者
颜景海
陈镁琳
叶曼曼
王松子
肖健
张式鸿
郑晓和
YAN Jinghai;CHEN Meilin;YE Manman;WANG Songzi;XIAO Jian;ZHANG Shihong;ZHENG Xiaohe(Department of Laboratory Medicine,the First Affiliated Hospital,Sun Yat-sen University,Guangzhou,Guangdong 510080,China;Guangzhou Yuexiu Center for Disease Control and Prevention,Guangzhou,Guangdong 510080,China)
出处
《热带医学杂志》
2025年第10期1429-1431,1439,共4页
Journal of Tropical Medicine
基金
国家自然科学基金(82000355)
吴阶平基金(320.6750.2023-06-89)。
关键词
华支睾吸虫
人芽囊原虫
流行病学
Clonorchis sinensis
Blastocystis hominis
Epidemiology
