摘要
随着人口老龄化加剧、环境风险增加、疾病谱系变化,居民的重大慢性疾病发病率持续上升,亟需依托科技手段实现相关疾病的早筛早诊、精准治疗、有效干预;粒子加速器作为多学科交叉集成的重要装备,广泛嵌入放射诊断、放射治疗、放射性药物制备、辐照消毒等生命健康关键场景,开展功能拓展与系统集成的价值突出。本文系统梳理了粒子加速器的技术特征与5类典型应用场景,总结了生命健康领域中粒子加速器的应用进展、前沿方向、发展策略以及技术、应用、政策维度面临的发展挑战,提出了诊断加速器的自主化与智能化、治疗加速器的国产替代、核药加速器的集成部署、以粒子加速器为核心的医疗产业平台等重点发展任务。可在构建闭环式政策协同机制、开展核心环节突破与系统集成、提升注册效率与医保适配性、培育协同创新生态并提升社会接受度等方面采取行动,精准推进生命健康领域中粒子加速器的技术攻关与应用拓展,增强我国高端医疗装备自主化发展能力。
With the intensification of population aging,increasing environmental risks,and evolving disease spectra,the incidence of major chronic diseases in China continues to rise.Addressing this challenge requires the adoption of advanced technologies to enable early screening and diagnosis,precision treatment,and effective intervention.As an essential multidisciplinary and integrative technology,particle accelerators have become deeply embedded in key life and health scenarios,such as radiation diagnostics,radiotherapy,radiopharmaceutical production,and irradiation sterilization,demonstrating significant potential for functional expansion and system integration.This study reviews the technical characteristics of particle accelerators and classifies five representative application scenarios in the life and health field.It summarizes the current progress,frontier trends,and strategic directions of accelerator applications,and analyzes the major challenges from the technological,application,and policy dimensions.Based on this,the study proposes several key development priorities,including the autonomous and intelligent development of diagnostic accelerators,domestic substitution of therapeutic accelerators,integrated deployment of nuclear medicine accelerators,and construction of medical platforms centered on accelerator technologies.To accelerate the translation and diffusion of accelerator technologies,the study further suggests actions such as establishing a closed-loop policy coordination mechanism,promoting breakthroughs in core components and system integration,enhancing regulatory registration efficiency and medical insurance adaptability,and fostering a collaborative innovation ecosystem with improved public acceptance.These efforts will advance the technological innovation and application expansion of particle accelerators in the life and health sector,and enhance China’s independent innovation capacity in high-end medical equipment.
作者
任冬林
张桓瑞
范国滨
羊奕伟
蔡寻
刘樑
Ren Donglin;Zhang Huanrui;Fan Guobin;Yang Yiwei;Cai Xun;Liu Liang(School of Economics and Management,Southwest University of Science and Technology,Mianyang 621010,Sichuan,China;Chinese Academy of Engineering Physics,Mianyang 621022,Sichuan,China)
出处
《中国工程科学》
北大核心
2025年第6期217-226,共10页
Strategic Study of CAE
基金
中国工程院咨询项目“我国新型工业化高质量发展体系构建的关键要素与实现路径研究”(2024-XZ-71)
“先进加速器重大工程领域面向人民健康的技术应用路径与政策研究”(2023-JB-09)
“宁夏与周边省区产业创新和科技创新融合发展研究”(2025BEL01008)。
关键词
粒子加速器
放射治疗
核素制备
硼中子俘获治疗
闪光治疗
诊疗一体化
particle accelerator
radiotherapy
radionuclide production
boron neutron capture therapy(BNCT)
FLASH radiotherapy
integrated diagnosis and treatment
