摘要
肺隐球菌病影像学表现多样,但以孤立性磨玻璃影为初始CT表现的病例报道较少,临床对其认识不足,容易误诊为肿瘤或结核,导致接受不必要的手术或抗结核治疗。本文报告1例无明显免疫缺陷的青年女性患者,其初始CT表现为右下肺孤立性磨玻璃影,病灶在近3个月内进展为实性结节,最终经肺穿刺活检确诊为肺隐球菌病,口服氟康唑治疗后痊愈。本文结合相关文献,回顾此类患者的临床特征和影像学演变规律,以期为临床医生提供参考。
Pulmonary cryptococcosis(PC)exhibits diverse imaging manifestations,but solitary ground-glass opacity(GGO)as the initial finding on computed tomography(CT)is rarely reported.Limited clinical awareness may lead to misdiagnosis as tumors or tuberculosis,often resulting in unnecessary surgical intervention or anti-tuberculosis therapy.This paper reports a young immunocompetent female patient whose initial CT revealed a solitary GGO in the right lower lobe of lung.Over the course of nearly three months,the lesion progressed to a solid nodule and was ultimately diagnosed as PC through percutaneous lung biopsy.The patient achieved complete recovery with oral fluconazole therapy.This paper reviews the clinical characteristics and imaging progression patterns of such patients by combining relevant literatures,aiming to provide a reference for clinicians.
作者
李果
庞敏
范庞双
王鹏
庞先琼
周国华
蒲洪山
刘思念
郭三君
LI Guo;PANG Min;FAN Pangshuang;WANG Peng;PANG Xianqiong;ZHOU Guo-hua;PU Hongshan;LIU Sinian;GUO Sanjun(Department of Pulmonary and Critical Care Medicine,Xichong County People’s Hospital,Nanchong 637200,China;Department of Thoracic Surgery,Xichong County People’s Hospital,Nanchong 637200,China;Department of Radiology,Xichong County People’s Hospital,Nanchong 637200,China;Department of Pathology,Xichong County People’s Hospital,Nanchong 637200,China;Department of Pathology,Sichuan Provincial Women’s and Children’s Hospital,The Affiliated Women’s and Children’s Hospital of Chengdu Medical College,Chengdu 610045,China)
出处
《中国感染控制杂志》
北大核心
2025年第12期1848-1850,共3页
Chinese Journal of Infection Control
关键词
肺隐球菌病
孤立性磨玻璃影
经皮肺穿刺活检
氟康唑
宏基因组二代测序
pulmonary cryptococcosis
solitary ground-glass opacity
percutaneous lung biopsy
fluconazole
metagenomic next-generation sequencing
