摘要
目的:探究内镜逆行胰胆管造影术(ERCP)治疗急性梗阻性化脓性胆管炎(AOSC)患者的效果。方法:选取2021年6月—2024年6月河北省人民医院收治的AOSC患者480例,按照就诊时间分为对照组(n=240,采取经皮经肝胆管引流术)与观察组(n=240,采取ERCP)。比较两组手术指标、临床疗效、肝功能指标及生活质量。结果:观察组手术及住院时间短于对照组(P<0.001),术中出血量与术后24 h视觉模拟评分法评分低于对照组(P<0.001);观察组手术成功率高于对照组(P<0.001),30 d病死率低于对照组(P=0.032);术前1 d、术后7 d,两组总胆红素、直接胆红素水平比较,无统计学差异(P>0.05);术后30 d,观察组活力状况、生理职能、情感职能、社会功能评分高于对照组(P<0.001)。结论:在AOSC的治疗中,ERCP的手术效果较经皮经肝胆管引流术好,其手术及住院时间短,术中出血量少,术后疼痛轻,手术成功率高,病死率低,可提高患者的生活质量。
Objective:To explore the effect of endoscopic retrograde cholangiopancreatography(ERCP)in the treatment of patients with acute obstructive suppurative cholangitis(AOSC).Methods:A total of 480 AOSC patients admitted to Hebei General Hospital from June 2021 to June 2024 were selected.According to the time of treatment,they were divided into the control group(n=240,undergoing percutaneous transhepatic biliary drainage)and the observation group(n=240,undergoing ERCP).The surgical indicators,clinical efficacy,liver function indicators and quality of life were compared between the two groups.Results:The operation time and the length of hospital stay in the observation group were shorter than those in the control group(P<0.001),and the intraoperative blood loss and visual analogue scale score at 24 h after surgery in the observation group were lower than those in the control group(P<0.001).The success rate of surgery in the observation group was higher than that in the control group(P<0.001),and the 30-d mortality rate in the observation group was lower than that in the control group(P=0.032).There were no statistically significant differences in the levels of total bilirubin and direct bilirubin between the two groups on 1 d before surgery and 7 d after surgery(P>0.05).On 30 d after surgery,the scores of vitality,physiological function,emotional function and social function in the observation group were higher than those in the control group(P<0.001).Conclusion:In the treatment of AOSC,ERCP has better surgical effect than percutaneous transhepatic biliary drainage.ERCP has shorter operation time and length of hospital stay,less intraoperative blood loss,milder postoperative pain,higher success rate of surgery and lower mortality rate,and can improve the quality of life of patients.
作者
王存凯
刘红玉
王丹丹
白云
Wang Cunkai;Liu Hongyu;Wang Dandan;Bai Yun(Hebei General Hospita1,Shijiazhuang 050000,Hebei Province,China;The Fourth Hospital of Hebei Medical University,Shijiazhuang 050011,Hebei Province,China)
出处
《中外医药研究》
2025年第31期13-15,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
基金
河北省2023年度医学科学研究课题(编号:20230019)。
关键词
急性梗阻性化脓性胆管炎
内镜逆行胰胆管造影术
经皮经肝胆管引流术
生活质量
−−Acute obstructive suppurative cholangitis
Endoscopic retrograde cholangiopancreatography
Percutaneous transhepatic biliary drainage
Quality of life
