摘要
To the Editor:Multi-pathogen detection has become increasingly important,given the increasing risk of circulating contagious pathogens due to global changes characterized by urbanization and habitat fragmentation.The coronavirus disease-2019(COVID-19)pandemic disrupted the epidemiology of some respiratory pathogens,possibly due to public health and social measures,as well as changes in healthcare-seeking behaviors and interactions between viruses.Multi-respiratory pathogen surveillance could be useful for adjusting disease prevention strategies and preventing potential outbreaks of existing and emerging respiratory infectious diseases.On the other hand,symptoms and disease severity differ among respiratory pathogen infections,[1]and coinfection might be associated with increased disease severity.[2]Some respiratory pathogens such as severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),influenza viruses(IFV),respiratory syncytial virus(RSV),and Streptococcus pneumoniae(S.pneumoniae)impose a high disease burden on populations but can be prevented by vaccines.Therefore,this study aimed to determine clinical manifestations and disease severity among patients testing positive for various pathogens to offer guidance on disease diagnosis,treatment,surveillance,and immunization strategies.
基金
supported by grants from the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(No.2022-I2M-CoV19-006)
the Science & Technology Fundamental Resources Investigation Program(No.2023FY100600)
the Investigator Initiated Study in Collaboration with Sanofi(No.FLU00152)
the Chongqing Science and Technology Bureau(Nos.CSTC2021jscx-gksb-N0005 and cstc2024ycjhbgzxm0224).
