摘要
目的探讨ST段时限和ST/QT值在鉴别肥厚型心肌病(hypertrophic cardiomyopathy,HCM)和高血压心室肥厚(hypertensive ventricular hypertrophy,HVH)中的临床应用价值。方法共入选98例受试者,其中45例为无心脏疾病的体检健康者(对照组),22例为HCM患者(HCM组),31例为HVH患者(HVH组)。所有受试者均接受心电图检查。比较各组ST段时限、QT间期及ST/QT值,并评估ST段时限及ST/QT对HCM与HVH诊断的敏感性及特异性。结果3组患者的ST段时限、ST/QT比较,差异均有统计学意义(均P<0.01)。与对照组相比,HCM组和HVH组的ST段时限及ST/QT值均显著升高(均P<0.01),而QT间期差异无统计学意义。诊断效能评估显示,ST段时限及ST/QT诊断HCM的敏感性分别为77.27%、86.36%,特异性分别为86.67%、77.78%,AUC值分别为0.847(P<0.01)、0.859(P<0.01);ST段时限及ST/QT诊断HVH的敏感性分别为64.52%、70.97%,特异性为97.78%、93.33%,AUC值分别为0.833(P<0.01)、0.849(P<0.01)。结论ST段时限和ST/QT均可作为HCM及HVH的诊断指标,且具有较高的特异性。
Objective To evaluate the clinical utility of ST-segment duration and ST/QT ratio in differentiating between hypertrophic cardiomyopathy(HCM)and hypertensive ventricular hypertrophy(HVH).Methods A total of 98 subjects were enrolled,including 45 patients without cardiac disease(control group),22 patients with HCM(HCM group),and 31 patients with HVH(HVH group).All participants underwent electrocardiogram(ECG)examinations.The ST-segment duration,QT interval,and ST/QT ratio were compared among the groups,while the diagnostic sensitivity and specificity of ST-segment duration and ST/QT for distinguishing HCM from HVH were assessed.Results Statistically significant differences were observed in ST-segment duration and ST/QT among the three groups(both P<0.01).Compared with the control group,both HCM and HVH groups exhibited significantly elevated ST-segment duration and ST/QT ratio(both P<0.01),while no statistically significant difference was found in the QT interval.Diagnostic efficiency evaluation revealed that the sensitivity of ST-segment duration and ST/QT for diagnosing HCM was 77.27%and 86.36%,respectively,with specificity of 86.67%and 77.78%,and AUC values of 0.847(P<0.01)and 0.859(P<0.01).For diagnosing HVH,the sensitivity of ST-segment duration and ST/QT was 64.52%and 70.97%,respectively,with specificity of 97.78%and 93.33%,and AUC values of 0.833(P<0.01)and 0.849(P<0.01),respectively.Conclusion Both ST-segment duration and ST/QT could serve as diagnostic indicators for HCM and HVH,with high specificity.
作者
张雯莉
周娜
张一凡
ZHANG Wenli;ZHOU Na;ZHANG Yifan(Office of Graduate Student Affairs,Xi'an Medical University,Xi'an Shaanxi 710021;Affiliated Cardiovascular Hospital,Xi'an No.9 Hospital,Xi'an Shaanxi 710054,China)
出处
《实用心电与临床诊疗》
2025年第6期787-791,共5页
PRACTICAL ELECTROCARDIOLOGY AND CLINICAL TREATMENT
基金
西安市创新能力强基计划—医学研究项目(22YXYJ0071)
西安市创新能力支撑计划—医学研究项目(23YXYJ0081)。
关键词
ST段时限
ST/QT
高血压心室肥厚
肥厚型心肌病
心电图
ST-segment duration
ST/QT
hypertensive ventricular hypertrophy
hypertrophic cardiomyopathy
electrocardiogram
