摘要
静脉血栓栓塞症(VTE)包括深静脉血栓形成(DVT)和肺栓塞(PE),其中PE多由DVT血栓脱落栓塞肺动脉引发,具有起病急骤、致死率高的特点。胆道恶性肿瘤(BTC)是消化系统侵袭性较强的恶性肿瘤,其全球发病率逐年上升,但因早期诊断困难,患者预后普遍较差。VTE作为BTC的重要并发症之一,显著缩短了患者生存时间。本文从流行病学、病理机制、风险因素、预防与治疗等方面,系统综述BTC合并VTE的近年研究进展,以期为临床实践提供参考。
Venous thromboembolism(VTE)includes deep vein thrombosis(DVT)and pulmonary embolism(PE),with PE predominantly arising from DVT-related thrombus embolization into the pulmonary circulation.PE is characterized by rapid onset and high mortality,posing significant clinical challenges.Biliary tract carcinoma(BTC)represents highly aggressive malignancies within the gastrointestinal system.The global incidence of BTC has been steadily increasing,yet patient prognosis remains poor,primarily due to the challenges associated with early detection.VTE,as a notable complication of BTC,markedly reduces patient survival.This article provides a comprehensive review of the current literature on the intersection of BTC-associated VTE,focusing on epidemiology,pathological mechanisms,risk factors,prevention and treatment,with the aim of offering valuable insights for clinical practice.
作者
孔红媛
董可心
王尉蓉
李振坤
KONG Hongyuan;DONG Kexin;WANG Weirong;LI Zhenkun(Department of Respiratory Medicine,The Second Affiliated Hospital of Kunming Medical University,Kunming 650101;Department of Oncology,Second Affiliated Hospital of Kunming Medical University,Kunming 650101,China)
出处
《临床肿瘤学杂志》
2025年第11期1133-1137,共5页
Chinese Clinical Oncology
基金
云南省教育厅科学研究基金项目(2022J0197)
昆明医科大学硕士研究生创新基金项目(2025S258)。
关键词
胆道恶性肿瘤
胆管癌
胆囊癌
静脉血栓栓塞症
肺栓塞
biliary tract carcinoma
cholangiocarcinoma
gallbladder cancers
venous thromboembolism
pulmonary embolism
