摘要
目的对比腹腔镜肝癌根治术与开腹手术治疗肝癌患者的短期疗效以及预后。方法选择2023年1月—2024年3月陕西中医药大学临床医学院收治的肝癌患者60例,随机分为对照组和观察组各30例。对照组采用开腹手术治疗,观察组采用腹腔镜肝癌根治术治疗,比较两组患者的各项围手术期指标。结果观察组手术时间、术后排气时间、术后拔管时间、绝对卧床时间、住院时间、肠鸣音恢复时间、排便时间均短于对照组,差异有统计学意义(P<0.05)。观察组C-反应蛋白、降钙素原、白介素-6和肿瘤坏死因子-α均低于对照组,差异有统计学意义(P<0.05)。观察组血清白蛋白高于对照组,而总胆红素、谷丙转氨酶、谷草转氨酶低于对照组,差异有统计学意义(P<0.05)。观察组肾上腺素、去甲肾上腺素、多巴胺均低于对照组,差异有统计学意义(P<0.05)。结论腹腔镜肝癌根治术治疗的短期疗效以及生存预后效果均优于开腹手术,这一优势体现在术后恢复、炎症状态、脏器损伤和应激多方面。
Objective To compare the short-term efficacy and prognosis of laparoscopic radical resection and open surgery for patients with liver cancer.Methods Sixty patients with liver cancer admitted to Clinical Medical College of Shaanxi University of Chinese Medicine from January 2023 to March 2024 were selected and divided into a control group(n=30)and an observation group(n=30),by a random number table method.The control group was treated with open surgery,while the observation group was treated with laparoscopic radical resection of liver cancer.The perioperative indicators of the two groups of patients were compared.Results After surgery,the observation group had shorter operation time,postoperative exhaust time,postoperative extubation time,absolute bed rest time,hospitalization time,bowel sound recovery time,and defecation time than the control group(P<0.05).The levels of C-reactive protein,procalcitonin,interleukin-6,and tumor necrosis factor-αin the observation group were lower than those in the control group(P<0.05).The serum albumin of the observation group was higher than that of the control group,while the total bilirubin,alanine aminotransferase,and aspartate aminotransferase were lower than those of the control group(P<0.05).The levels of adrenaline,norepinephrine,and dopamine in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The shortterm efficacy and survival prognosis of laparoscopic radical resection for liver cancer are superior to those of open surgery,with this advantage being manifested in various aspects such as postoperative recovery,inflammatory status,organ damage,and stress.
作者
张凯迪
ZHANG Kaidi(Clinical Medical College,Shaanxi University of Chinese Medicine,Xianyang 712046,Shaanxi Province,China)
出处
《中国实用乡村医生杂志》
2025年第10期69-72,共4页
Chinese Practical Journal of Rural Doctor
关键词
肝癌
腹腔镜
开腹手术
疗效
预后
Liver Cancer
Laparoscopy
Open Surgery
Therapeutic Effect
Prognosis
