摘要
眼肌型重症肌无力(OMG)是重症肌无力最常见的一种临床表型,患者常因上睑下垂和(或)复视等症状首诊于眼科。OMG的临床表现具有高度异质性,易与多种眼外肌麻痹性疾病相混淆,从而导致误诊或漏诊。值得注意的是,约半数以上OMG患者在发病后2年内可能向全身型转化,严重时甚至危及生命。因此,实现对OMG的早期精准识别与诊断,不仅有助于缓解患者眼部症状、提升其生活质量,还能通过适时干预降低全身转化的风险。然而,当前临床实践中OMG的诊疗仍普遍存在延迟与滞后,亟待通过规范诊疗路径、建立多学科协作模式,以改善患者整体预后。
Ocular myasthenia gravis(OMG)is the most common clinical phenotype of myasthenia gravis,and patients often first present to ophthalmology clinics due to symptoms such as ptosis and/or diplopia.The clinical manifestations of OMG are highly heterogeneous and can easily be confused with various extraocular muscle paralysis disorders,leading to misdiagnosis or underdiagnosis.Notably,more than half of OMG patients may progress to generalized myasthenia gravis within two years after disease onset,which can be life-threatening in severe cases.Therefore,achieving early and accurate identification and diagnosis of OMG not only alleviate patients'ocular symptoms and improve their quality of life,but also reduces the risk of generalized conversion through timely intervention.However,in current clinical practice,the diagnosis and management of OMG are often delayed,highlighting the urgent need to standardize diagnostic and management pathways and establish multidisciplinary collaboration models to improve overall patient prognosis.
作者
吴松笛
蔺雪梅
魏世辉
Wu Songdi;Lin Xuemei;Wei Shihui(Department of Neuro-Ophthalmology,The First Hospital of Xi’an(The First Affiliated Hospital of Northwest University),Xi’an 710002,China;Department of Neuro-Ophthalmology,Chinese PLA General Hospital,Beijing 100853,China)
出处
《中华眼底病杂志》
北大核心
2025年第12期903-906,共4页
Chinese Journal of Ocular Fundus Diseases
关键词
眼肌型重症肌无力
早期识别
诊疗
述评
Ocular myasthenia gravis
Early identification
Diagnosis and management
Editorial
