摘要
系统性红斑狼疮(SLE)可继发卵巢储备功能下降、月经异常及不良妊娠结局等妇产科疾病。基于“体脏合痹”理论,提出SLE继发妇产科疾病的核心在于“体痹”与“脏痹”相互传变,共同作用于“女子胞”。生理上,女子胞通过经络、血脉与体、脏构成内外相合的网络;病理上,正虚则体脏失濡,毒瘀则病邪循冲任等经脉内扰胞宫,胞宫之痹亦可外应体表、加重体脏损伤。因此,SLE继发妇产科疾病的病机演变存在“体痹为先-体痹及脏-体脏合痹”的动态轨迹。治疗上,强调以和正调衡为总纲,调脏安体养胞为主导,以体养脏为协同,实现体脏同治,凸显了“体脏合痹”理论在防治SLE继发妇产科疾病中的指导价值。
Systemic lupus erythematosus(SLE)may lead to secondary gynecological and obstetric disorders such as decreased ovarian reserve function,menstrual abnormalities,and adverse pregnancy outcomes.Based on"bi(痹)of both body and viscera"theory,this paper proposed that the core mechanism of SLE secondary gynecological and obstetric diseases lies in the mutual transformation between"body bi"and"viscera bi",which together affect the uterus.Physiologically,uterus forms an internal-external network with the body and viscera through the meridians and blood vessels.Pathologically,when the healthy qi is deficient,nourishment of the body and viscera is impaired;when toxins and stasis accumulate,pathogenic factors disturb the uterus through the chong(冲)and ren(任)meri-dians.The resulting obstruction in the uterus can,in turn,manifest externally and aggravate damage to the body and viscera.Therefore,the pathogenesis of SLE secondary gynecological and obstetric diseases follows a dynamic trajectory of"body bi first,body bi affecting viscera,and then bi of both body and viscera".In treatment,the principle of harmonizing and balancing the healthy qi is emphasized.The main approach is to regulate the viscera,stabilize the body,and nourish the uterus,with the coordination of nourishing the viscera through the body,thereby achieving simultaneous treatment of both body and viscera.This highlights the guiding significance of the"bi of both body and viscera"theory in preventing and treating SLE secondary gynecological and obstetric diseases.
作者
徐惠
姜泉
夏聪敏
张柔曼
巩勋
姚传辉
刘子夏
杨煜辰
马协丽
XU Hui;JIANG Quan;XIA Congmin;ZHANG Rouman;GONG Xun;YAO Chuanhui;LIU Zixia;YANG Yuchen;MA Xieli(Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing,100053)
出处
《中医杂志》
北大核心
2025年第23期2438-2442,共5页
Journal of Traditional Chinese Medicine
基金
中央高水平中医医院临床研究和成果转化能力提升项目(HLCMHPP2023014)
北京市重大疑难疾病中西医协同攻关项目(2023BJSZDYNJBXTGG-003)。
关键词
系统性红斑狼疮
体脏合痹
卵巢储备功能
月经不调
妊娠结局
systemic lupus erythematosus
bi(痹)of both body and viscera
ovarian reserve function
menstrual disorders
pregnancy outcomes
