摘要
目的分析某三甲综合医院多重耐药菌(multidrug-resistant organism,MDRO)感染分布特征及趋势情况,为提高医院MDRO感染防控能力提供科学依据。方法采用回顾性调查法,分析2021—2023年医院送检标本培养分离出的MDRO总体情况及分布特征。结果2021—2023年从培养分离出的14466株病原菌中检测出1379株MDRO,检出率为9.53%;其中,病原菌以大肠埃希菌(27.7%)、肺炎克雷伯菌(22.85%)和金黄色葡萄球菌(15.55%)为主,MDRO则以ESBL(54.53%)、MRSA(21.46%)和MRCNS(16.46%)为主。标本来源以尿液(36.11%)和痰液(21.54%)为主,其次为上呼吸道(14.00%)、脓液(10.44%)和血液(7.32%)。MDRO检测呈阳性送检标本主要来源于儿科(11.75%)、肾病内科(11.68%)、普外科(10.95%)、泌尿外科(9.86%)、内分泌科(7.11%)等科室。结论某三甲综合医院MDRO防控依然面临较为严峻的挑战,需要通过进一步完善院感防控措施、加强宣传教育、严格规范抗菌药物使用等,降低医院感染风险。
Objective To conduct an in-depth analysis of the distribution characteristics and trends of multidrug resistant organism(MDRO)infections in a tertiary general hospital,providing a scientific basis for enhancing MDRO containment capabilities.Methods A retrospective study was performed on MDRO isolates from clinical specimens between 2021 and 2023,analyzing epidemiological profiles and distribution patterns.Results Among 14,466 pathogenic isolates,1,379 MDRO strains(9.53%)were detected.Predominant pathogens:Escherichia coli(27.7%),Klebsiella pneumoniae(22.85%),Staphylococcus aureus(15.55%);dominant MDRO types:ESBL-producing strains(54.53%),MRSA(21.46%),MRCNS(16.46%);specimen sources:urine(36.11%),sputum(21.54%),upper respiratory tract(14.00%),pus(10.44%),blood(7.32%);high-risk departments(MDRO-positive specimens):pediatrics(11.75%),nephrology(11.68%),general surgery(10.95%),urology(9.86%),endocrinology(7.11%).Conclusion MDRO containment remains challenging in this tertiary hospital.Mitigation requires strengthening infection control protocols,enhancing antimicrobial stewardship,and implementing targeted staff training.
作者
梁燕
马玲飞
梁帆
LIANG Yan;MA Ling-fei;LIANG Fan(Department of Medical Laboratory,Wuzhong Peoplees Hospital,Wuzhong,Ningxia 751100,China;Nursing Department,Wuzhong Peoples Hospital,Wuzhong,Ningxia 751100,China)
出处
《医药论坛杂志》
2025年第20期2187-2191,2196,共6页
Journal of Medical Forum
关键词
多重耐药菌
医院感染
监测
防控措施
Multidrug-resistant organism
Nosocomial infection
Monitor
Preventive and control measures
